All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals
Bergs A, Liewald J, Rodriguez-Rozada S, Liu Q, Wirt C, Bessel A, Zeitzschel N, Durmaz H, Nozownik A, Dill H, Jospin M, Vierock J, Bargmann C, Hegemann P, Wiegert J, Gottschalk A
NAT COMMUN. 2023;14(1):1939.

Mice heterozygous for an osteogenesis imperfecta-linked MBTPS2 variant display a compromised subchondral osteocyte lacunocanalicular network associated with abnormal articular cartilage
Danyukova T, Alimy A, Velho R, Yorgan T, Di Lorenzo G, von Kroge S, Tidow H, Wiegert J, Hermans-Borgmeyer I, Schinke T, Rolvien T, Pohl S
BONE. 2023;177:.

A flexible and versatile system for multi-color fiber photometry and optogenetic manipulation
Formozov A, Dieter A, Wiegert J
CELL REP METHODS. 2023;3(3):100418.

Sensitive multicolor indicators for monitoring norepinephrine in vivo
Kagiampaki Z, Rohner V, Kiss C, Curreli S, Dieter A, Wilhelm M, Harada M, Duss S, Dernic J, Bhat M, Zhou X, Ravotto L, Ziebarth T, Wasielewski L, Sönmez L, Benke D, Weber B, Bohacek J, Reiner A, Wiegert J, Fellin T, Patriarchi T
NAT METHODS. 2023;20(9):1426-1436.

Dissociating instructive from permissive roles of brain circuits with reversible neural activity manipulations
Quintana D, Bounds H, Brown J, Wang M, Bhatla N, Wiegert J, Adesnik H
bioRxiv. 2023.

Modulating cardiac physiology in engineered heart tissue with the bidirectional optogenetic tool BiPOLES
Schwarzová B, Stüdemann T, Sönmez M, Rössinger J, Pan B, Eschenhagen T, Stenzig J, Wiegert J, Christ T, Weinberger F
PFLUG ARCH EUR J PHY. 2023;475(12):1463-1477.

A bistable inhibitory OptoGPCR for multiplexed optogenetic control of neural circuits
Wietek J, Nozownik A, Pulin M, Saraf-Sinik I, Matosevich N, Malan D, Brown B, Dine J, Levy R, Litvin A, Regev N, Subramaniam S, Bitton E, Benjamin A, Copits B, Sasse P, Rost B, Schmitz D, Soba P, Nir Y, Wiegert J, Yizhar O
bioRxiv. 2023.

Spike-timing-dependent plasticity rewards synchrony rather than causality
Anisimova M, van Bommel B, Wang R, Mikhaylova M, Wiegert J, Oertner T, Gee C
CEREB CORTEX. 2022;33(1):23-34.

Vesicular release probability sets the strength of individual Schaffer collateral synapses
Dürst C, Wiegert J, Schulze C, Helassa N, Török K, Oertner T
NAT COMMUN. 2022;13(1):.

Calcium imaging and electrophysiology of hippocampal activity under anesthesia and natural sleep in mice
Formozov A, Chini M, Dieter A, Yang W, Pöpplau J, Hanganu-Opatz I, Wiegert J
SCI DATA. 2022;9(1):1-11.

A flexible and versatile system for multicolor fiber photometry and optogenetic manipulation
Formozov A, Dieter A, Wiegert J
bioRxiv. 2022;1-48.

A neuropeptidergic circuit gates selective escape behavior of Drosophila larvae
Imambocus B, Zhou F, Formozov A, Wittich A, Tenedini F, Hu C, Sauter K, Macarenhas Varela E, Herédia F, Casimiro A, Macedo A, Schlegel P, Yang C, Miguel-Aliaga I, Wiegert J, Pankratz M, Gontijo A, Cardona A, Soba P
CURR BIOL. 2022;32(1):149-163.e8.

Next generation genetically encoded fluorescent sensors for serotonin
Kubitschke M, Müller M, Wallhorn L, Pulin M, Mittag M, Pollok S, Ziebarth T, Bremshey S, Gerdey J, Claussen K, Renken K, Groß J, Gneiße P, Meyer N, Wiegert J, Reiner A, Fuhrmann M, Masseck O
NAT COMMUN. 2022;13(1):.

Orthogonally-polarized excitation for improved two-photon and second-harmonic-generation microscopy, applied to neurotransmitter imaging with GPCR-based sensors
Pulin M, Stockhausen K, Masseck O, Kubitschke M, Busse B, Wiegert J, Oertner T
BIOMED OPT EXPRESS. 2022;13(2):777-790.

Aion is a bistable anion-conducting channelrhodopsin that provides temporally extended and reversible neuronal silencing
Rodriguez-Rozada S, Wietek J, Tenedini F, Sauter K, Dhiman N, Hegemann P, Soba P, Wiegert J
COMMUN BIOL. 2022;5(1):.

Temporally extended and reversible neuronal silencing with Aion
Rodriguez-Rozada S, Wietek J, Tenedini F, Sauter K, Hegemann P, Soba P, Wiegert J
2022.

Contractile Force of Transplanted Cardiomyocytes Actively Supports Heart Function After Injury
Stüdemann T, Rössinger J, Manthey C, Geertz B, Srikantharajah R, von Bibra C, Shibamiya A, Köhne M, Wiehler A, Wiegert J, Eschenhagen T, Weinberger F
CIRCULATION. 2022;146(15):1159-1169.

Selective optogenetic control of Gq signaling using human Neuropsin
Wagdi A, Malan D, Sathyanarayanan U, Beauchamp J, Vogt M, Zipf D, Beiert T, Mansuroglu B, Dusend V, Meininghaus M, Schneider L, Kalthof B, Wiegert J, König G, Kostenis E, Patejdl R, Sasse P, Bruegmann T
NAT COMMUN. 2022;13(1):.

Targeting Noradrenergic Neurons of the Locus Coeruleus: A Comparison of Model Systems and Strategies
Wissing C, Maheu M, Wiegert S, Dieter A
2022.

Efficient optogenetic silencing of neurotransmitter release with a mosquito rhodopsin
Mahn M, Saraf-Sinik I, Patil P, Pulin M, Bitton E, Karalis N, Bruentgens F, Palgi S, Gat A, Dine J, Wietek J, Davidi I, Levy R, Litvin A, Zhou F, Sauter K, Soba P, Schmitz D, Lüthi A, Rost B, Wiegert J, Yizhar O
NEURON. 2021;109(10):1621-1635.e8.

Linking emotional valence and anxiety in a mouse insula-amygdala circuit
Nicolas C, Ju A, Wu Y, Eldirdiri H, Delcasso S, Jacky D, Supiot L, Fornari C, Vérité A, Masson M, Rodriguez-Rozada S, Wiegert J, Beyeler A
2021.

Contractile force of transplanted cardiomyocytes contributes to heart function after injury
Stüdemann T, Rössinger J, Manthey C, Geertz B, Srikantharajah R, Bibra C, Shibamiya A, Köhne M, Wiehler A, Wiegert J, Eschenhagen T, Weinberger F
2021.

BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons
Vierock J, Rodriguez-Rozada S, Dieter A, Pieper F, Sims R, Tenedini F, Bergs A, Bendifallah I, Zhou F, Zeitzschel N, Ahlbeck J, Augustin S, Sauter K, Papagiakoumou E, Gottschalk A, Soba P, Emiliani V, Engel A, Hegemann P, Wiegert J
NAT COMMUN. 2021;12(1):4527.

Anesthetics fragment hippocampal network activity, alter spine dynamics, and affect memory consolidation
Yang W, Chini M, Pöpplau J, Formozov A, Dieter A, Piechocinski P, Rais C, Morellini F, Sporns O, Hanganu-Opatz I, Wiegert J
PLOS BIOL. 2021;19(4):e3001146.

The vesicular release probability sets the strength of individual Schaffer collateral synapses
Dürst C, Wiegert J, Schulze C, Helassa N, Torok K, Oertner T
2020.

Freeze-frame imaging of synaptic activity using SynTagMA
Perez-Alvarez A, Fearey B, O'Toole R, Yang W, Arganda-Carreras I, Lamothe-Molina P, Moeyaert B, Mohr M, Panzera L, Schulze C, Schreiter E, Wiegert J, Gee C, Hoppa M, Oertner T
NAT COMMUN. 2020;11(1):2464.

Imbalanced cellular metabolism compromises cartilage homeostasis and joint function in a mouse model of mucolipidosis type III gamma
Westermann L, Fleischhauer L, Vogel J, Jenei-Lanzl Z, Floriano Ludwig N, Schau L, Morellini F, Baranowsky A, Yorgan T, Di Lorenzo G, Schweizer M, de Souza Pinheiro B, Guarany N, Sperb-Ludwig F, Visioli F, Oliveira Silva T, Soul J, Hendrickx G, Wiegert J, Schwartz I, Clausen-Schaumann H, Zaucke F, Schinke T, Pohl S, Danyukova T
DIS MODEL MECH. 2020;13(11):.

Monosynaptic hippocampal-prefrontal projections contribute to spatial memory consolidation in mice
Binder S, Mölle M, Lippert M, Bruder R, Aksamaz S, Ohl F, Wiegert J, Marshall L
J NEUROSCI. 2019;39(35):6978-6991.

High-speed imaging of glutamate release with genetically encoded sensors
Dürst C, Wiegert J, Helassa N, Kerruth S, Coates C, Schulze C, Geeves M, Török K, Oertner T
NAT PROTOC. 2019;14(5):1401-1424.

MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins
Oppermann J, Fischer P, Silapetere A, Liepe B, Rodriguez-Rozada S, Flores-Uribe J, Peter E, Keidel A, Vierock J, Kaufmann J, Broser M, Luck M, Bartl F, Hildebrandt P, Wiegert J, Béjà O, Hegemann P, Wietek J
NAT COMMUN. 2019;10(1):3315.

Designer Drugs for Designer Receptors: Unlocking the Translational Potential of Chemogenetics
Yizhar O, Wiegert J
TRENDS PHARMACOL SCI. 2019;40(6):362-364.

Ultrafast glutamate sensors resolve high-frequency release at Schaffer collateral synapses
Helassa N, Dürst C, Coates C, Kerruth S, Arif U, Schulze C, Wiegert J, Geeves M, Oertner T, Török K
P NATL ACAD SCI USA. 2018;115(21):5594-5599.

Crystal structure of the red light-activated channelrhodopsin Chrimson
Oda K, Vierock J, Oishi S, Rodriguez-Rozada S, Taniguchi R, Yamashita K, Wiegert J, Nishizawa T, Hegemann P, Nureki O
NAT COMMUN. 2018;9(1):3949.

The fate of hippocampal synapses depends on the sequence of plasticity-inducing events
Wiegert J, Pulin M, Gee C, Oertner T
ELIFE. 2018;7:e39151.

Author Correction: Anion-conducting channelrhodopsins with tuned spectra and modified kinetics engineered for optogenetic manipulation of behavior
Wietek J, Rodriguez-Rozada S, Tutas J, Tenedini F, Grimm C, Oertner T, Soba P, Hegemann P, Wiegert J
SCI REP-UK. 2018;8(1):4765.

Layer-specific optogenetic activation of pyramidal neurons causes beta-gamma entrainment of neonatal networks
Bitzenhofer S, Ahlbeck J, Wolff A, Wiegert J, Gee C, Oertner T, Hanganu-Opatz I
NAT COMMUN. 2017;8:14563.

Preparation of Slice Cultures from Rodent Hippocampus
Gee C, Ohmert I, Wiegert J, Oertner T
Cold Spring Harbor protocols. 2017;2017(2):pdb.prot094888.

Single-Cell Electroporation of Neurons
Wiegert J, Gee C, Oertner T
Cold Spring Harbor protocols. 2017;2017(2):pdb.prot094904.

Stimulating Neurons with Heterologously Expressed Light-Gated Ion Channels
Wiegert J, Gee C, Oertner T
Cold Spring Harbor protocols. 2017;2017(2):pdb.top089714.

Viral Vector-Based Transduction of Slice Cultures
Wiegert J, Gee C, Oertner T
Cold Spring Harbor protocols. 2017;2017(2):pdb.prot094896.

Silencing Neurons: Tools, Applications, and Experimental Constraints
Wiegert J, Mahn M, Prigge M, Printz Y, Yizhar O
NEURON. 2017;95(3):504-529.

Anion-conducting channelrhodopsins with tuned spectra and modified kinetics engineered for optogenetic manipulation of behavior
Wietek J, Rodriguez-Rozada S, Tutas J, Tenedini F, Grimm C, Oertner T, Soba P, Hegemann P, Wiegert J
SCI REP-UK. 2017;7(1):14957.

How (not) to silence long-range projections with light
Wiegert J, Oertner T
NAT NEUROSCI. 2016;19(4):527-8.

Automated analysis of spine dynamics on live CA1 pyramidal cells
Blumer C, Vivien C, Genoud C, Perez-Alvarez A, Wiegert S, Vetter T, Oertner T
MED IMAGE ANAL. 2015;19(1):87-97.

Neighborly synapses help each other out
Wiegert S, Oertner T
NAT NEUROSCI. 2015;18(3):326-7.

An improved chloride-conducting channelrhodopsin for light-induced inhibition of neuronal activity in vivo
Wietek J, Beltramo R, Scanziani M, Hegemann P, Oertner T, Simon Wiegert J
SCI REP-UK. 2015;5:14807.

Imaging of molecular surface dynamics in brain slices using single-particle tracking
Biermann B, Sokoll S, Klueva J, Missler M, Wiegert S, Sibarita J, Heine M
NAT COMMUN. 2014;5:3024.

Conversion of channelrhodopsin into a light-gated chloride channel
Wietek J, Wiegert J, Adeishvili N, Schneider F, Watanabe H, Tsunoda S, Vogt A, Elstner M, Oertner T, Hegemann P
SCIENCE. 2014;344(6182):409-12.

Long-term depression triggers the selective elimination of weakly integrated synapses
Wiegert J, Oertner T
P NATL ACAD SCI USA. 2013;110(47):E4510-9.

Multiple dynamic representations in the motor cortex during sensorimotor learning.
Huber D, Gutnisky D, Peron S, O'Connor D, Wiegert J, Tian L, Oertner T, Looger L, Svoboda K
NATURE. 2012;484(7395):473-478.

Structural dynamics of the cell nucleus: basis for morphology modulation of nuclear calcium signaling and gene transcription.
Queisser G, Wiegert J, Bading H
NUCLEUS-PHILA. 2011;2(2):98-104.

Activity-dependent calcium signaling and ERK-MAP kinases in neurons: a link to structural plasticity of the nucleus and gene transcription regulation.
Wiegert J, Bading H
CELL CALCIUM. 2011;49(5):296-305.

Shapeshifting for memory : Biochemical and electrical signaling in dendritic spines
Wiegert S, Oertner T
e-Neuroforum. 2011;2(1):6-12.

AMPA receptors gate spine Ca(2+) transients and spike-timing-dependent potentiation.
Holbro N, Grunditz A, Wiegert J, Oertner T
P NATL ACAD SCI USA. 2010;107(36):15975-15980.

A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons.
Wiegert J, Hofmann F, Bading H, Bengtson C
BMC NEUROSCI. 2009;10:124.

Synaptic activity induces dramatic changes in the geometry of the cell nucleus: interplay between nuclear structure, histone H3 phosphorylation, and nuclear calcium signaling.
Wittmann M, Queisser G, Eder A, Wiegert J, Bengtson C, Hellwig A, Wittum G, Bading H
J NEUROSCI. 2009;29(47):14687-14700.

Diffusion and not active transport underlies and limits ERK1/2 synapse-to-nucleus signaling in hippocampal neurons.
Wiegert J, Bengtson C, Bading H
J BIOL CHEM. 2007;282(40):29621-29633.

Letzte Aktualisierung aus dem FIS: 26.11.2024 - 23:32 Uhr