Sex differences in lipidomic and bile acid plasma profiles in patients with and without coronary artery disease
Bay B, Fuh M, Rohde J, Worthmann A, Goßling A, Arnold N, Koester L, Lorenz T, Blaum C, Kirchhof P, Blankenberg S, Seiffert M, Brunner F, Waldeyer C, Heeren J
LIPIDS HEALTH DIS. 2024;23(1):197.

The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells
Behler-Janbeck F, Baranowsky A, Schinke T, Jaeckstein M, Worthmann A, Fuh M, Gunasekaran K, Tiegs G, Amling M, Schinke T, Heeren J
FRONT ENDOCRINOL. 2024;15:1392418.

The TRPM2 ion channel regulates metabolic and thermogenic adaptations in adipose tissue of cold-exposed mice
Benzi A, Heine M, Spinelli S, Salis A, Worthmann A, Diercks B, Astigiano C, Pérez Mato R, Memushaj A, Sturla L, Vellone V, Damonte G, Jaeckstein M, Koch-Nolte F, Mittrücker H, Guse A, De Flora A, Heeren J, Bruzzone S
FRONT ENDOCRINOL. 2024;14:1251351.

Time-resolved role of P2X4 and P2X7 during CD8+ T cell activation
Brock V, Lory N, Möckl F, Birus M, Stähler T, Woelk L, Jaeckstein M, Heeren J, Koch-Nolte F, Rissiek B, Mittrücker H, Guse A, Werner R, Diercks B
FRONT IMMUNOL. 2024;15:1258119.

The importance of Ca2+ microdomains for the adaptive immune response
Diercks B
BBA-MOL CELL RES. 2024;1871(5):119710.

The dream to become a midwife: a qualitative study on students‘ motivation to study midwifery
Groene O, Mielke I, Vogel D, Knorr M
Zeitschrift für Hebammenwissenschaft. 2024;12(1):21-28.

Multimodal image-guided laser ablation system for precise 3D tissue sampling and subsequent analysis of biomolecules for cancer research
Hahn J, Moritz M, Walter A, Wieck T, Moustafa A, Mansour W, Harms C, Stenzel P, Heeren J, Haider M, Lange T, Schlüter H
2024. Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXII. Tárnok A, Houston J (Hrsg.). 1. Aufl. Bellingham, Washington: SPIE , .

CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates de novo lipogenesis in adipose tissue
Jaeckstein M, Schulze I, Zajac M, Heine M, Mann O, Pfeifer A, Heeren J
FRONT IMMUNOL. 2024;14:1308456.

Measuring personal characteristics in applicants to German medical schools: Piloting an online Situational Judgement Test with an open-ended response format
Knorr M, Mielke I, Amelung D, Safari M, Groene O, Breil S, MacIntosh A
GMS J MED EDU. 2024;41(3):Doc30.

Apoptotic cell identity induces distinct functional responses to IL-4 in efferocytic macrophages
Liebold I, Al Jawazneh A, Casar C, Lanzloth C, Leyk S, Hamley M, Wong M, Kylies D, Gräfe S, Edenhofer I, Aranda-Pardos I, Kriwet M, Haas H, Krause J, Hadjilaou A, Schromm A, Richardt U, Eggert P, Tappe D, Weidemann S, Ghosh S, Krebs C, A-Gonzalez N, Worthmann A, Lohse A, Huber S, Rothlin C, Puelles V, Jacobs T, Gagliani N, Bosurgi L
SCIENCE. 2024;384(6691):eabo7027.

Obesity and diabetes mellitus are associated with SARS-CoV-2 outcomes without influencing signature genes of extrapulmonary immune compartments at the RNA level
Lücke J, Böttcher M, Nawrocki M, Meins N, Schnell J, Heinrich F, Bertram F, Sabihi M, Seeger P, Pfaff M, Notz S, Blankenburg T, Zhang T, Kempski J, Reeh M, Wolter S, Mann O, Lütgehetmann M, Hackert T, Izbicki J, Duprée A, Huber S, Ondruschka B, Giannou A
HELIYON. 2024;10(2):e24508.

Generation and characterization of antagonistic anti-human CD39 nanobodies
Menzel S, Duan Y, Hambach J, Albrecht B, Wendt-Cousin D, Winzer R, Tolosa E, Rissiek A, Guse A, Haag F, Magnus T, Koch-Nolte F, Rissiek B
FRONT IMMUNOL. 2024;15:1328306.

Deep Image Prior for Spatio-temporal Fluorescence Microscopy Images: DECO-DIP
Meyer L, Woelk L, Gee C, Lohr C, Arcot Kannabiran S, Diercks B, Werner R
2024. Bildverarbeitung für die Medizin 2024. Maier A, Deserno T, Handels H, Maier-Hein K, Palm C, Tolxdorff T (Hrsg.). 1. Aufl. Springer Vieweg, 322-327.

Predicting undergraduate OSCE performance using traditional and construct-driven situational judgment tests at admission
Mielke I, Breil S, Hissbach J, Ehrhardt M, Knorr M
ADV HEALTH SCI EDUC. 2024 [Epub ahead of print].

Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes
Moschandrea C, Kondylis V, Evangelakos I, Herholz M, Schneider F, Schmidt C, Yang M, Ehret S, Heine M, Jaeckstein M, Szczepanowska K, Schwarzer R, Baumann L, Bock T, Nikitopoulou E, Brodesser S, Krüger M, Frezza C, Heeren J, Trifunovic A, Pasparakis M
NATURE. 2024;625(7994):385-392.

Neues Zulassungsverfahren Humanmedizin: höhere individuelle Gerechtigkeit, aber Verstärkung des Landarztmangels?
Mueller-Hilke B, Finger C, Hampe W
BUNDESGESUNDHEITSBLA. 2024;67(2):225-232.

2'-deoxy-ADPR activates human TRPM2 faster than ADPR and thereby induces higher currents at physiological Ca2+ concentrations
Pick J, Sander S, Etzold S, Rosche A, Tidow H, Guse A, Fliegert R
FRONT IMMUNOL. 2024;15:1294357.

The effects of language proficiency and awareness of time limit in animated vs. text-based situational judgment tests
Rabe M, Groene O, von Bernstorff C, Knorr M
BMC MED EDUC. 2024;24(1):540.

EPAC1 enhances brown fat growth and beige adipogenesis
Reverte-Salisa L, Siddig S, Hildebrand S, Yao X, Zurkovic J, Jaeckstein M, Heeren J, Lezoualc'h F, Krahmer N, Pfeifer A
NAT CELL BIOL. 2024;26(1):113-123.

HERC5 downregulation in non-small cell lung cancer is associated with altered energy metabolism and metastasis
Schneegans S, Löptien J, Mojzisch A, Loreth D, Kretz O, Raschdorf C, Hanssen A, Gocke A, Siebels B, Gunasekaran K, Ding Y, Oliveira-Ferrer L, Brylka L, Schinke T, Schlüter H, Paatero I, Voß H, Werner S, Pantel K, Wikman H
J EXP CLIN CANC RES. 2024;43(1):110.

DARTS: an open-source Python pipeline for Ca2+ microdomain analysis in live cell imaging data
Woelk L, Kovacevic D, Husseini H, Förster F, Gerlach F, Möckl F, Altfeld M, Guse A, Diercks B, Werner R
FRONT IMMUNOL. 2024;14:1299435.

Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use
Worthmann A, Ridder J, Piel S, Evangelakos I, Musfeldt M, Voß H, O'Farrell M, Fischer A, Adak S, Sundd M, Siffeti H, Haumann F, Kloth K, Bierhals T, Heine M, Pertzborn P, Pauly M, Scholz J, Kundu S, Fuh M, Neu A, Tödter K, Hempel M, Knippschild U, Semenkovich C, Schlüter H, Heeren J, Scheja L, Kubisch C, Schlein C
NAT COMMUN. 2024;15(1):45.

Septins provide microenvironment sensing and cortical actomyosin partitioning in motile amoeboid T lymphocytes
Zhovmer A, Manning A, Smith C, Nguyen A, Prince O, Sáez P, Ma X, Tsygankov D, Cartagena-Rivera A, Singh N, Singh R, Tabdanov E
SCI ADV. 2024;10(1):eadi1788.

Integration naturwissenschaftlicher und medizinischer Grundlagen im Hamburger Modellstudiengang Zahnmedizin iMED DENT
Bender R, Bruhn N, Eisenbarth S, Lemke R, Pantke C, Hampe W, Schwoerer A
BUNDESGESUNDHEITSBLA. 2023;66(12):1353-1362.

Guidelines for mouse and human DC functional assays
Clausen B, Amon L, Backer R, Berod L, Bopp T, Brand A, Burgdorf S, Chen L, Da M, Distler U, Dress R, Dudziak D, Dutertre C, Eich C, Gabele A, Geiger M, Ginhoux F, Giusiano L, Godoy G, Hamouda A, Hatscher L, Heger L, Heidkamp G, Hernandez L, Jacobi L, Kaszubowski T, Kong W, Lehmann C, Lopez Lopez T, Mahnke K, Nitsche D, Renkawitz J, Reza R, Saez P, Schlautmann L, Schmitt M, Seicher A, Sielaff M, Sparwasser T, Stoitzer P, Tchitashvili G, Tenzer S, Tochoedo N, Vurnek D, Zink F, Hieronymus T
EUR J IMMUNOL. 2023;53(12):e2249925.

Acute Deletion of the Glucocorticoid Receptor in Hepatocytes Disrupts Postprandial Lipid Metabolism in Male Mice
Correia C, Præstholm S, Havelund J, Pedersen F, Siersbæk M, Ebbesen M, Gerhart-Hines Z, Heeren J, Brewer J, Larsen S, Blagoev B, Færgeman N, Grøntved L
ENDOCRINOLOGY. 2023;164(10):.

Live-cell imaging identifies cAMP microdomains regulating β-adrenoceptor-subtype-specific lipolytic responses in human white adipocytes
De Jong K, Ehret S, Heeren J, Nikolaev V
CELL REP. 2023;42(5):112433.

Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22
Giannou A, Kempski J, Shiri A, Lücke J, Zhang T, Zhao L, Zazara D, Cortesi F, Riecken K, Amezcua Vesely M, Low J, Xu H, Kaffe E, Garcia-Perez L, Agalioti T, Yamada Y, Jungraithmayr W, Zigmond E, Karstens K, Steglich B, Wagner J, Konczalla L, Carambia A, Schulze K, von Felden J, May P, Briukhovetska D, Bedke T, Brockmann L, Starzonek S, Lange T, Koch C, Riethdorf S, Pelczar P, Böttcher M, Sabihi M, Huber F, Reeh M, Grass J, Wahib R, Seese H, Stüben B, Fard-Aghaie M, Duprée A, Scognamiglio P, Plitzko G, Meiners J, Soukou S, Wittek A, Manthey C, Maroulis I, Arck P, Perez D, Gao B, Zarogiannis S, Strowig T, Pasqualini R, Arap W, Gosálvez J, Kobold S, Prinz I, Guse A, Tachezy M, Ghadban T, Heumann A, Li J, Melling N, Mann O, Izbicki J, Pantel K, Schumacher U, Lohse A, Flavell R, Gagliani N, Huber S
IMMUNITY. 2023;56(1):125-142.e12.

T cell Ca2+ microdomains through the lens of computational modeling
Gil Montoya D, Ornelas-Guevara R, Diercks B, Guse A, Dupont G
FRONT IMMUNOL. 2023;14:1235737.

German Physicians and Medical Students Do Not Represent the Population They Serve
Groene O, Huelmann T, Hampe W, Emami P
HEALTHCARE-BASEL. 2023;11(12):.

Enzymology of Ca2+-Mobilizing Second Messengers Derived from NAD: From NAD Glycohydrolases to (Dual) NADPH Oxidases
Guse A
CELLS-BASEL. 2023;12(4):.

NAADP-Evoked Ca2+ Signaling: The DUOX2-HN1L/JPT2-Ryanodine Receptor 1 Axis
Guse A
2023. Endolysosomal Voltage-Dependent Cation Channels. Wahl-Schott C, Biel M (Hrsg.). 1. Aufl. Cham: Springer, Cham, 57-70.

Der erste Modellstudiengang Zahnmedizin in Deutschland – iMED DENT
Guse A, Beikler T, Heydecke G, Gosau M, Kahl-Nieke B
BUNDESGESUNDHEITSBLA. 2023;66(12):1345-1352.

Biochemie hoch2: und Molekularbiologie 2. Auflage
Hampe W, Fluhrer R, Kouz K, Averbeck B, Dankwardt A, Duszenko M, Eberharter A, Harter C, Höppner S, Kindler S, Korber P, Kreienkamp H, Neumann S, Nielsen P, Salat D, Schling P, Unterleitner C, Wild-Bode C
2023.

A liquid chromatography-tandem mass spectrometry based method for the quantification of adenosine nucleotides and NAD precursors and products in various biological samples
Hiefner J, Rische J, Bunders M, Worthmann A
FRONT IMMUNOL. 2023;14:1250762.

2-Methoxyestradiol-3,17-O,O-bis-sulfamate inhibits store-operated Ca2+ entry in T lymphocytes and prevents experimental autoimmune encephalomyelitis
Hosang L, Löhndorf A, Dohle W, Rosche A, Marry S, Diercks B, Müller-Kirschbaum L, Flügel L, Potter B, Odoardi F, Guse A, Flügel A
BBA-MOL CELL RES. 2023;1870(6):119485.

Chronic pain in osteoarthritis of the hip is associated with selective cognitive impairment
Kazim M, Strahl A, Moritz S, Arlt S, Niemeier A
ARCH ORTHOP TRAUM SU. 2023;143(4):2189-2197.

The actin bundling activity of ITPKA mainly accounts for its migration-promoting effect in lung cancer cells
Küster L, Paraschiakos T, Karakurt K, Schumacher U, Diercks B, Windhorst S
BIOSCIENCE REP. 2023;43(2):.

Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens
Kylies D, Zimmermann M, Haas F, Schwerk M, Kuehl M, Brehler M, Czogalla J, Hernandez L, Konczalla L, Okabayashi Y, Menzel J, Edenhofer I, Mezher S, Aypek H, Dumoulin B, Wu H, Hofmann S, Kretz O, Wanner N, Tomas N, Krasemann S, Glatzel M, Kuppe C, Kramann R, Banjanin B, Schneider R, Urbschat C, Arck P, Gagliani N, van Zandvoort M, Wiech T, Grahammer F, Sáez P, Wong M, Bonn S, Huber T, Puelles V
NAT NANOTECHNOL. 2023;18(4):336-342.

TREM2 Regulates the Removal of Apoptotic Cells and Inflammatory Processes during the Progression of NAFLD
Liebold I, Meyer S, Heine M, Kuhl A, Witt J, Eissing L, Fischer A, Koop A, Kluwe J, Wiesch J, Wehmeyer M, Knippschild U, Scheja L, Heeren J, Bosurgi L, Worthmann A
CELLS-BASEL. 2023;12(3):.

The lysosomal LAMTOR / Ragulator complex is essential for nutrient homeostasis in brown adipose tissue
Liebscher G, Vujic N, Schreiber R, Heine M, Krebiehl C, Duta-Mare M, Lamberti G, de Smet C, Hess M, Eichmann T, Hölzl S, Scheja L, Heeren J, Kratky D, Huber L
MOL METAB. 2023;71:101705.

TNFα aggravates detrimental effects of SARS-CoV-2 infection in the liver
Lücke J, Nawrocki M, Schnell J, Meins N, Heinrich F, Zhang T, Bertram F, Sabihi M, Böttcher M, Blankenburg T, Pfaff M, Notz S, Kempski J, Reeh M, Wolter S, Mann O, Izbicki J, Lütgehetmann M, Duprée A, Giannou A, Ondruschka B, Huber S
FRONT IMMUNOL. 2023;14:1151937.

Daily dynamics of grandiose narcissism: distribution, stability, and trait relations of admiration and rivalry states and state contingencies
Mota S, Mielke I, Kroencke L, Geukes K, Nestler S, Back M
EUR J PERSONALITY. 2023;37(2):207-222.

Short-term dietary changes can result in mucosal and systemic immune depression
Siracusa F, Schaltenberg N, Kumar Y, Lesker T, Steglich B, Liwinski T, Cortesi F, Frommann L, Diercks B, Bönisch F, Fischer A, Scognamiglio P, Pauly M, Casar C, Cohen Y, Pelczar P, Agalioti T, Delfs F, Worthmann A, Wahib R, Jagemann B, Mittrücker H, Kretz O, Guse A, Izbicki J, Lassen K, Strowig T, Schweizer M, Villablanca E, Elinav E, Huber S, Heeren J, Gagliani N
NAT IMMUNOL. 2023;24(9):1473-1486.

Lipidome Analysis of Oropharyngeal Tumor Tissues Using Nanosecond Infrared Laser (NIRL) Tissue Sampling and Subsequent Mass Spectrometry
Stadlhofer R, Moritz M, Fuh M, Heeren J, Zech H, Clauditz T, Schlüter H, Betz C, Eggert D, Böttcher A, Hahn J
INT J MOL SCI. 2023;24(9):.

Potential role of the bitter taste receptor T2R14 in the prolonged survival and enhanced chemoresponsiveness induced by apigenin
Stern L, Boehme L, Goetz M, Nitschke C, Giannou A, Zhang T, Güngör C, Reeh M, Izbicki J, Fliegert R, Hausen A, Giese N, Hackert T, Niv M, Heinrich S, Gaida M, Ghadban T
INT J ONCOL. 2023;62(1):.

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion
van Zwol W, Rimbert A, Wolters J, Smit M, Bloks V, Kloosterhuis N, Huijkman N, Koster M, Tharehalli U, de Neck S, Bournez C, Fuh M, Kuipers J, Rajan S, de Bruin A, Ginsberg H, van Westen G, Hussain M, Scheja L, Heeren J, Zimmerman P, van de Sluis B, Kuivenhoven J
HEPATOLOGY. 2023;78(5):1418-1432.

Adhesion to laminin-1 and collagen IV induces the formation of Ca2+ microdomains that sensitize mouse T cells for activation
Weiß M, Hernandez L, Gil Montoya D, Löhndorf A, Krüger A, Kopdag M, Uebler L, Landwehr M, Nawrocki M, Huber S, Woelk L, Werner R, Failla A, Flügel A, Dupont G, Guse A, Diercks B
SCI SIGNAL. 2023;16(790):eabn9405.

Calcium channel β3 subunit regulates ATP-dependent migration of dendritic cells
Woo M, Ufer F, Sonner J, Belkacemi A, Tintelnot J, Sáez P, Krieg P, Mayer C, Binkle-Ladisch L, Engler J, Bauer S, Kursawe N, Vieira V, Mannebach S, Freichel M, Flockerzi V, Vargas P, Friese M
SCI ADV. 2023;9(38):.

Fallbeispiele und Grundlagen aus der Prävention, Biochemie und Physiologie
Zyriax B, Schwoerer A, Guse A
2023. Fachbuch Schwangerschaft und Stillzeit. Zyriax B (Hrsg.). 1. Aufl. München: Elsevier GmbH, 7-48.

Human dental pulp cells modulate CD8+ T cell proliferation and efficiently degrade extracellular ATP to adenosine in vitro
Ahmadi P, Yan M, Bauche A, Smeets R, Müller C, Koch-Nolte F, Haag F, Fliegert R, Kluwe L, Schulze Zur Wiesch J, Hartjen P
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Role of Liver CD38 in the Regulation of Metabolic Pathways during Cold-Induced Thermogenesis in Mice
Benzi A, Spinelli S, Sturla L, Heine M, Fischer A, Koch-Nolte F, Mittrücker H, Guse A, De Flora A, Heeren J, Bruzzone S
CELLS-BASEL. 2022;11(23):.

Predicting Actual Social Skill Expression from Personality and Skill Self-Concepts
Breil S, Mielke I, Ahrens H, Geldmacher T, Sensmeier J, Marschall B, Back M
J INTELL-BASEL. 2022;10(3):.

P2X4 and P2X7 are essential players in basal T cell activity and Ca2+ signaling milliseconds after T cell activation
Brock V, Wolf I, Er-Lukowiak M, Lory N, Stähler T, Woelk L, Mittrücker H, Müller C, Koch-Nolte F, Rissiek B, Werner R, Guse A, Diercks B
SCI ADV. 2022;8(5):.

Final-year medical students' self-assessment of facets of competence for beginning residents
Bußenius L, Harendza S, van den Bussche H, Selch S
BMC MED EDUC. 2022;22(1):.

Evaluating the Global Rating scale's psychometric properties to assess communication skills of undergraduate medical students in video-recorded simulated patient encounters
Bußenius L, Kadmon M, Berberat P, Harendza S
PATIENT EDUC COUNS. 2022;105(3):750-755.

Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1
Dieckmann S, Strohmeyer A, Willershäuser M, Maurer S, Wurst W, Marschall S, de Angelis M, Kühn R, Worthmann A, Fuh M, Heeren J, Köhler N, Pauling J, Klingenspor M
AM J PHYSIOL-ENDOC M. 2022;322(2):E85-E100.

Cold-Induced Lipoprotein Clearance in Cyp7b1-Deficient Mice
Evangelakos I, Kuhl A, Baguhl M, Schlein C, John C, Rohde J, Heine M, Worthmann A
FRONT CELL DEV BIOL. 2022;10(10):836741.

Lysosomal acid lipase promotes endothelial proliferation in cold-activated adipose tissue
Fischer A, Jaeckstein M, Heeren J
ADIPOCYTE. 2022;11(1):28-33.

Validation of the ComCare index for rater-based assessment of medical communication and interpersonal skills
Gärtner J, Bußenius L, Schick K, Prediger S, Kadmon M, Berberat P, Harendza S
PATIENT EDUC COUNS. 2022;105(4):1004-1008.

A Critical Role of the IL-22-IL-22 Binding Protein Axis in Hepatocellular Carcinoma
Giannou A, Lücke J, Kleinschmidt D, Shiri A, Steglich B, Nawrocki M, Zhang T, Zazara D, Kempski J, Zhao L, Giannou O, Agalioti T, Brockmann L, Bertram F, Sabihi M, Böttcher M, Ewald F, Schulze K, von Felden J, Machicote A, Maroulis I, Arck P, Graß J, Mercanoglu B, Reeh M, Wolter S, Tachezy M, Seese H, Theodorakopoulou M, Lykoudis P, Heumann A, Uzunoglu F, Ghadban T, Mann O, Izbicki J, Li J, Duprée A, Melling N, Gagliani N, Huber S
CANCERS. 2022;14(24):.

Three-Dimensional Model of Sub-Plasmalemmal Ca2+ Microdomains Evoked by T Cell Receptor/CD3 Complex Stimulation
Gil D, Diercks B, Guse A, Dupont G
FRONT MOL BIOSCI. 2022;9:.

How good are medical students at communicating risk? An implementation study at three German medical schools
Groene O, Bergelt C, Ehrhardt M
PATIENT EDUC COUNS. 2022;105(1):128-135.

Attitude and communication skills of German medical students
Groene O, Ehrhardt M, Bergelt C
BMC RES NOTES. 2022;15(1):11.

Reliability and validity of new online selection tests for midwifery students
Groene O, Knorr M, Vogel D, Hild C, Hampe W
MIDWIFERY. 2022;106:.

Associations between communication OSCE performance and admission interviews in medical education
Groene O, Mielke I, Knorr M, Ehrhardt M, Bergelt C
PATIENT EDUC COUNS. 2022;105(7):2270 - 2275.

NAADP Signaling: New Kids on the Block
Guse A
CELLS-BASEL. 2022;11(6):.

Tuning TPC2
Guse A
CELL CALCIUM. 2022;108:.

Metabolic Turnover Studies to Quantify Energy Uptake by Thermogenic Adipose Tissues of Mice
Heine M, Corban C, Heeren J
2022. Brown Adipose Tissue. 1. Aufl. New York, NY: HUMANA PRESS INC, 107-118.

Macrophage invasion here, there and everywhere
Hernandez L, Sáez P
SIGNAL TRANSDUCT TAR. 2022;7(1):.

Der Einfluss von Elternstatus, erlebter Unterstützung und Befristung auf das Belastungserleben und die Karriereentwicklung von Ärztinnen und Ärzten am Ende der Weiterbildung
Kocalevent R, Grande N, Selch S, Nehls S, Meyer J, Boczor S, Scherer M, Bussche van den H
GESUNDHEITSWESEN. 2022;84(3):208-214.

Zum Einfluss von Partnerschaft auf Burnout und Gratifikationskrisen bei Ärzten und Ärztinnen in fachärztlicher Weiterbildung unter Berücksichtigung der Aufteilung von beruflicher Tätigkeit und Hausarbeit
Kocalevent R, Schmitz A, Selch S, Boczor S, Scherer M, van den Bussche H
Z PSYCHOSOM MED PSYC. 2022;68(4):340-349.

TRPM2 Is Not Required for T-Cell Activation and Differentiation
Lory N, Nawrocki M, Corazza M, Schmid J, Schumacher V, Bedke T, Menzel S, Koch-Nolte F, Guse A, Huber S, Mittrücker H
FRONT IMMUNOL. 2022;12:.

c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease
Marín T, Dulcey A, Campos F, de la Fuente C, Acuña M, Castro J, Pinto C, Yañez M, Cortez C, McGrath D, Sáez P, Gorshkov K, Zheng W, Southall N, Carmo-Fonseca M, Marugán J, Alvarez A, Zanlungo S
FRONT CELL DEV BIOL. 2022;10:.

Assessing distinguishable social skills in medical admission: does construct-driven development solve validity issues of situational judgment tests?
Mielke I, Breil S, Amelung D, Espe L, Knorr M
BMC MED EDUC. 2022;22(1):293.

Can Different Admissions to Medical School Predict Performance of Non-Technical Skill Performance in Simulated Clinical Settings?
Moll-Khosrawi P, Hampe W, Schulte-Uentrop L, Zöllner C, Zimmermann S, Huelmann T
HEALTHCARE-BASEL. 2022;11(1):.

Fat Quantification in Dual-Layer Detector Spectral Computed Tomography: Experimental Development and First In-Patient Validation
Molwitz I, Campbell G, Yamamura J, Knopp T, Toedter K, Fischer R, Wang Z, Busch A, Ozga A, Zhang S, Lindner T, Sevecke F, Grosser M, Adam G, Szwargulski P
INVEST RADIOL. 2022;57(7):463-469.

The Calcium-Sensing Receptor Stabilizes Podocyte Function in Proteinuric Humans and Mice
Mühlig A, Steingröver J, Heidelbach H, Wingerath M, Sachs W, Hermans-Borgmeyer I, Meyer-Schwesinger C, Choi H, Lim B, Patry C, Hoffmann G, Endlich N, Bracke K, Weiß M, Guse A, Lassé M, Rinschen M, Braun F, Huber T, Puelles V, Schmitt C, Oh J
KIDNEY INT. 2022;101(6):1186-1199.

Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine
Niemann B, Haufs-Brusberg S, Puetz L, feickert m, Jaeckstein M, Hoffmann A, Zurkovic J, Heine M, Trautmann E, Müller C, Tönies A, Schlein C, Jafari A, Eltzsching H, Gnad T, Blüher M, Krahmer N, Kovacs P, Heeren J, Pfeifer A
NATURE. 2022;609(7926):361–368.

Diagnostic potential of extracellular vesicles in meningioma patients
Ricklefs F, Maire C, Wollmann K, Dührsen L, Fita K, Sahm F, Herold-Mende C, von Deimling A, Kolbe K, Holz M, Bergmann L, Fuh M, Schlüter H, Alawi M, Reimer R, Sven P, Glatzel M, Westphal M, Lamszus K
NEURO-ONCOLOGY. 2022;24(12):2078-2090.

cADPR Does Not Activate TRPM2
Riekehr W, Sander S, Pick J, Tidow H, Bauche A, Guse A, Fliegert R
INT J MOL SCI. 2022;23(6):.

A Gas Chromatography Mass Spectrometry-Based Method for the Quantification of Short Chain Fatty Acids
Rohde J, Fuh M, Evangelakos I, Pauly M, Schaltenberg N, Siracusa F, Gagliani N, Tödter K, Heeren J, Worthmann A
METABOLITES. 2022;12(2):.

The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn2+ -binding domain essential for structural integrity and channel activity
Sander S, Pick J, Gattkowski E, Fliegert R, Tidow H
PROTEIN SCI. 2022;31(6):.

Novel Adipose Tissue Targets to Prevent and Treat Atherosclerosis
Scheja L, Heeren J
2022. Prevention and Treatment of Atherosclerosis. von Eckardstein A, Binder C (Hrsg.). 1. Aufl. Cham: Springer, 289-310.

Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice
Schepanski S, Chini M, Sternemann V, Urbschat C, Thiele K, Sun T, Zhao Y, Poburski M, Woestemeier A, Thieme M, Zazara D, Alawi M, Fischer N, Heeren J, Vladimirov N, Woehler A, Puelles V, Bonn S, Gagliani N, Hanganu-Opatz I, Arck P
NAT COMMUN. 2022;13(1):.

CMYA5 is a novel interaction partner of FHL2 in cardiac myocytes
Stathopoulou K, Schnittger J, Raabe J, Fleischer F, Mangels N, Piasecki A, Findlay J, Hartmann K, Krasemann S, Schlossarek S, Uebeler J, Wixler V, Blake D, Baillie G, Carrier L, Ehler E, Cuello F
FEBS J. 2022;289(15):4622-4645.

Mid-term improvement of cognitive performance after total hip arthroplasty in patients with osteoarthritis of the hip: A prospective cohort study
Strahl A, Kazim M, Kattwinkel N, Hauskeller W, Moritz S, Arlt S, Niemeier A
BONE JOINT J. 2022;104-B(3):331-340.

Increased concentrations of conjugated bile acids are associated with osteoporosis in PSC patients
Stürznickel J, Behler-Janbeck F, Baranowsky A, Schmidt T, Schwinge D, John C, Lohse A, Schramm C, Heeren J, Schinke T, Amling M
SCI REP-UK. 2022;12(1):.

Role of Endothelial Cell Lipoprotein Lipase for Brown Adipose Tissue Lipid and Glucose Handling
Thiemann E, Schwaerzer G, Evangelakos I, Fuh M, Jaeckstein M, Behrens J, Nilsson S, Kumari M, Scheja L, Pfeifer A, Heeren J, Heine M
FRONT PHYSIOL. 2022;13:.

P2X7 is expressed on human innate-like T lymphocytes and mediates susceptibility to ATP-induced cell death
Winzer R, Serracant-Prat A, Brock V, Pinto-Espinoza C, Rissiek B, Amadi M, Eich N, Rissiek A, Schneider E, Magnus T, Guse A, Diercks B, Koch-Nolte F, Tolosa E
EUR J IMMUNOL. 2022;52(11):1805-1818.

Dekonvolution von Mikroskopiedaten bei niedrigem Signal-Rausch-Verhältnis
Woelk L, Diercks B, Werner R
BIOspektrum. 2022;2022(28):720-722.

MALDI MSI for a fresh view on atherosclerotic plaque lipids
Worthmann A, Bartelt A
PFLUG ARCH EUR J PHY. 2022;474(2):185-186.

Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans
Zickler M, Stanelle-Bertram S, Ehret S, Heinrich F, Lange P, Schaumburg B, Kouassi N, Beck S, Jaeckstein M, Mann O, Krasemann S, Schroeder M, Jarczak D, Nierhaus A, Kluge S, Peschka M, Schlüter H, Renné T, Pueschel K, Kloetgen A, Scheja L, Ondruschka B, Heeren J, Gabriel G
CELL METAB. 2022;34(1):1-2.

Mouse CD38-Specific Heavy Chain Antibodies Inhibit CD38 GDPR-Cyclase Activity and Mediate Cytotoxicity Against Tumor Cells
Baum N, Eggers M, Koenigsdorf J, Menzel S, Hambach J, Staehler T, Fliegert R, Kulow F, Adam G, Haag F, Bannas P, Koch-Nolte F
FRONT IMMUNOL. 2021;12:.

Daratumumab and Nanobody-Based Heavy Chain Antibodies Inhibit the ADPR Cyclase but not the NAD+ Hydrolase Activity of CD38-Expressing Multiple Myeloma Cells
Baum N, Fliegert R, Bauche A, Hambach J, Menzel S, Haag F, Bannas P, Koch-Nolte F
CANCERS. 2021;13(1):.

Role of CD38 in Adipose Tissue: Tuning Coenzyme Availability?
Benzi A, Grozio A, Spinelli S, Sturla L, Guse A, De Flora A, Zocchi E, Heeren J, Bruzzone S
NUTRIENTS. 2021;13(11):.

CD38 downregulation modulates NAD+ and NADP(H) levels in thermogenic adipose tissues
Benzi A, Sturla L, Heine M, Fischer A, Spinelli S, Magnone M, Sociali G, Parodi A, Fenoglio D, Emionite L, Koch-Nolte F, Mittrücker H, Guse A, De Flora A, Zocchi E, Heeren J, Bruzzone S
BBA-MOL CELL BIOL L. 2021;1866(1):158819.

Are different medical school admission tests associated with the outcomes of a simulation-based OSCE?
Bußenius L, Harendza S
BMC MED EDUC. 2021;21(1):263.

Nanoparticle-mediated targeting of autoantigen peptide to cross-presenting liver sinusoidal endothelial cells protects from CD8 T-cell-driven autoimmune cholangitis
Carambia A, Gottwick C, Schwinge D, Stein S, Digigow R, Şeleci M, Mungalpara D, Heine M, Schuran F, Corban C, Lohse A, Schramm C, Heeren J, Herkel J
IMMUNOLOGY. 2021;162(4):452-463.

The first junior European Calcium Society meeting: calcium research across scales, Kingdoms and countries
Diercks B, Jensen H, Chalmers S, Coode E, Vaughan M, Tadayon R, Sáez P, Davis F, Brohus M
BBA-MOL CELL RES. 2021;1868(6):118999.

CD4+ Tregs may be essential for solving astrocyte glial scar deadlock
Edwar-Mickael M, Kubick N
NEURAL REGEN RES. 2021;16(12):2563.

Role of bile acids in inflammatory liver diseases
Evangelakos I, Heeren J, Verkade E, Kuipers F
SEMIN IMMUNOPATHOL. 2021;43(4):577-590.

Oxysterol 7-α Hydroxylase (CYP7B1) Attenuates Metabolic-Associated Fatty Liver Disease in Mice at Thermoneutrality
Evangelakos I, Schwinge D, Worthmann A, John C, Roeder N, Pertzborn P, Behrens J, Schramm C, Scheja L, Heeren J
CELLS-BASEL. 2021;10(10):2656.

Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation
Fischer A, Jaeckstein M, Gottschling K, Heine M, Sass F, Mangels N, Schlein C, Worthmann A, Bruns O, Yuan Y, Zhu H, Chen O, Ittrich H, Nilsson S, Stefanicka P, Ukropec J, Balaz M, Dong H, Sun W, Reimer R, Scheja L, Heeren J
CELL METAB. 2021;33(3):547-564.e7.

Analysis of ligand binding and resulting conformational changes in pyrophosphatase NUDT9
Gattkowski E, Rutherford T, Möckl F, Bauche A, Sander S, Fliegert R, Tidow H
FEBS J. 2021;288(23):6769-6782.

Three-Dimensional Model of Sub-Plasmalemmal Ca2+ Microdomains Evoked by the Interplay Between ORAI1 and InsP3 Receptors
Gil D, Guse A, Dupont G
FRONT IMMUNOL. 2021;12:.

Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation
Gu F, Krüger A, Roggenkamp H, Alpers R, Lodygin D, Jaquet V, Möckl F, Hernandez C L, Winterberg K, Bauche A, Rosche A, Grasberger H, Kao J, Schetelig D, Werner R, Schröder K, Carty M, Bowie A, Huber S, Meier C, Mittrücker H, Heeren J, Krause K, Flügel A, Diercks B, Guse A
SCI SIGNAL. 2021;14(709):.

Mechanisms and functions of calcium microdomains produced by ORAI channels, d-myo-inositol 1,4,5-trisphosphate receptors, or ryanodine receptors
Guse A, Gil Montoya D, Diercks B
PHARMACOL THERAPEUT. 2021;223:107804.

Spatio-temporal feature learning with reservoir computing for T-cell segmentation in live-cell Ca2+ fluorescence microscopy
Hadaeghi F, Diercks B, Schetelig D, Damicelli F, Wolf I, Werner R
SCI REP-UK. 2021;11(1):.

Pannexin Channel Regulation of Cell Migration: Focus on Immune Cells
Harcha P, López-López T, Palacios A, Sáez P
FRONT IMMUNOL. 2021;12:.

General population’s knowledge about the anatomical locations of organs and medical terms today and 50 years ago: a replication study
Harendza S, Münter A, Bußenius L, Bittner A
GMS J MED EDU. 2021;38(5):Doc94.

Isthmin 1 - a novel insulin-like adipokine
Heeren J, Scheja L
NAT REV ENDOCRINOL. 2021;17(12):709-710.

Metabolic-associated fatty liver disease and lipoprotein metabolism
Heeren J, Scheja L
MOL METAB. 2021;50:101238.

Trends of Anger and Physical Aggression in Russian Women During COVID-19 Lockdown
Klimovich-Mickael A, Kubick N, Milanesi E, Dobre M, Łazarczyk M, Wijas B, Sacharczuk M, Mickael M
Global Women's Health. 2021;2:698151.

Berufsverlaufs- und Lebenszufriedenheit von Ärztinnen in fachärztlicher Weiterbildung mit Kindern im Vergleich zu ihren männlichen Kollegen - Eine longitudinale Untersuchung im Rahmen der KarMed-Studie
Kocalevent R, Pawlik J, Selch S, Nehls S, Meyer J, Boczor S, Scherer M, Bussche van den H
Z EVIDENZ FORTBILD Q. 2021;161:50-56.

Investigation of Evolutionary History and Origin of the Tre1 Family Suggests a Role in Regulating Hemocytes Cells Infiltration of the Blood-Brain Barrier
Kubick N, Klimovich P, Bieńkowska I, Poznanski P, Łazarczyk M, Sacharczuk M, Mickael M
INSECTS. 2021;12(10):.

Interleukins and Interleukin Receptors Evolutionary History and Origin in Relation to CD4+ T Cell Evolution
Kubick N, Klimovich P, Flournoy P, Bieńkowska I, Łazarczyk M, Sacharczuk M, Bhaumik S, Mickael M, Basu R
GENES-BASEL. 2021;12(6):813.

2-Methoxyestradiol and its derivatives inhibit store-operated Ca2+ entry in T cells: identification of a new and potent inhibitor
Löhndorf A, Hosang L, Dohle W, Odoardi F, Waschkowski S, Rosche A, Bauche A, Winzer R, Tolosa E, Windhorst S, Marry S, Flügel A, Potter B, Diercks B, Guse A
BBA-MOL CELL RES. 2021;1868(6):118988.

Rationalizing heptadecaphobia: TH 17 cells and associated cytokines in cancer and metastasis
Lücke J, Shiri A, Zhang T, Kempski J, Giannou A, Huber S
FEBS J. 2021;288(24):6942-6971.

Genome-wide methylation profiling of glioblastoma cell-derived extracellular vesicle DNA allows tumor classification
Maire C, Fuh M, Kaulich K, Fita K, Stevic I, Heiland D, Welsh J, Jones J, Görgens A, Ricklefs T, Dührsen L, Sauvigny T, Joosse S, Reifenberger G, Pantel K, Glatzel M, Miklosi A, Felce J, Caselli M, Pereno V, Reimer R, Schlüter H, Westphal M, Schüller U, Lamszus K, Ricklefs F
NEURO-ONCOLOGY. 2021;23(7):1087-1099.

Paracellular and Transcellular Leukocytes Diapedesis Are Divergent but Interconnected Evolutionary Events
Mickael M, Kubick N, Klimovich P, Flournoy P, Bieńkowska I, Sacharczuk M
GENES-BASEL. 2021;12(2):.

Do Narcissists Self-Enhance? Disentangling the Associations Between Narcissism and Positive Versus Enhanced Self-Views Across Aspects of Narcissism, Content Domains, and Comparison Criteria
Mielke I, Humberg S, Leckelt M, Geukes K, Back M
SOC PSYCHOL PERS SCI. 2021;12(5):580-592.

Understanding Why All Types of Motivation Are Necessary in Advanced Anaesthesiology Training Levels and How They Influence Job Satisfaction: Translation of the Self-Determination Theory to Healthcare
Moll-Khosrawi P, Zimmermann S, Zoellner C, Schulte-Uentrop L
HEALTHCARE-BASEL. 2021;9(3):.

Trans-Ned 19-Mediated Antagonism of Nicotinic Acid Adenine Nucleotide—Mediated Calcium Signaling Regulates Th17 Cell Plasticity in Mice
Nawrocki M, Lory N, Bedke T, Stumme F, Diercks B, Guse A, Meier C, Gagliani N, Mittrücker H, Huber S
CELLS-BASEL. 2021;10(11):.

Editorial: The Versatile Role of Nicotinamide Adenine Dinucleotide in Immunity
Rissiek B, Guse A, Adriouch S, Bruzzone S
FRONT IMMUNOL. 2021;12:810280.

Comment on “Mice Lacking the Purinergic Receptor P2X5 Exhibit Defective Inflammasome Activation and Early Susceptibility to Listeria monocytogenes”
Rissiek B, Heeren J, Koch-Nolte F, Mittrücker H, Magnus T
J IMMUNOL. 2021;206(4):.

HN1L/JPT2: A signaling protein that connects NAADP generation to Ca2+ microdomain formation
Roggenkamp H, Khansahib I, Hernandez C L, Zhang Y, Lodygin D, Krüger A, Gu F, Möckl F, Löhndorf A, Wolters V, Woike D, Rosche A, Bauche A, Schetelig D, Werner R, Schlüter H, Failla A, Meier C, Fliegert R, Walseth T, Flügel A, Diercks B, Guse A
SCI SIGNAL. 2021;14(675):.

Changing scientific meetings for the better
Sarabipour S, Khan A, Seah Y, Mwakilili A, Mumoki F, Sáez P, Schwessinger B, Debat H, Mestrovic T
NAT HUM BEHAV. 2021;5(3):296-300.

TFEB-deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality
Sass F, Schlein C, Jaeckstein M, Pertzborn P, Schweizer M, Schinke T, Ballabio A, Scheja L, Heeren J, Fischer A
MOL METAB. 2021;47:101173.

Endothelial Lipase Is Involved in Cold-Induced High-Density Lipoprotein Turnover and Reverse Cholesterol Transport in Mice
Schaltenberg N, John C, Heine M, Haumann F, Rinninger F, Scheja L, Heeren J, Worthmann A
FRONT CARDIOVASC MED. 2021;8:628235.

Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution
Schlein C, Fischer A, Sass F, Worthmann A, Tödter K, Jaeckstein M, Behrens J, Lynes M, Kiebish M, Narain N, Bussberg V, Jespersen N, Nielsen S, Scheele C, Schweizer M, Braren I, Bartelt A, Tseng Y, Heeren J, Scheja L
CELL REP. 2021;34(2):108624.

Spinocerebellar ataxia type 14: refining clinicogenetic diagnosis in a rare adult-onset disorder
Schmitz-Hübsch T, Lux S, Bauer P, Brandt A, Schlapakow E, Greschus S, Scheel M, Gärtner H, Kirlangic M, Gras V, Timmann D, Synofzik M, Giorgetti A, Carloni P, Shah J, Schöls L, Kopp U, Bußenius L, Oberwahrenbrock T, Zimmermann H, Pfueller C, Kadas E, Rönnefarth M, Grosch A, Endres M, Amunts K, Paul F, Doss S, Minnerop M
ANN CLIN TRANSL NEUR. 2021;8(4):774-789.

CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression
Schneider E, Winzer R, Rissiek A, Ricklefs I, Meyer-Schwesinger C, Ricklefs F, Bauche A, Behrends J, Reimer R, Brenna S, Wasielewski H, Lauten M, Rissiek B, Puig B, Cortesi F, Magnus T, Fliegert R, Müller C, Gagliani N, Tolosa E
NAT COMMUN. 2021;12(1):5911.

Self-reported health literacy and medication adherence in older adults: a systematic review
Schönfeld M, Pfisterer-Heise S, Bergelt C
BMJ OPEN. 2021;11(12):.

Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice
Schuran F, Lommetz C, Steudter A, Ghallab A, Wieschendorf B, Schwinge D, Zuehlke S, Reinders J, Heeren J, Lohse A, Schramm C, Herkel J, Carambia A
CELL MOL GASTROENTER. 2021;11(2):371-388.

Eine Abstimmung mit den Füßen gegen die Spezialisierung in der Inneren Medizin? - Zur Attraktivität der internistischen Fachrichtungen im Verlauf der ärztlichen Weiterbildung.
Selch S, Boczor S, Meyer J, Kocalevent R, Scherer M, Bussche van den H
GESUNDHEITSWESEN. 2021;83(10):854-859.

On the attractiveness of working as a GP and rural doctor including admission pathways to medical school – results of a German nationwide online survey among medical students in their “Practical Year”
Selch S, Pfisterer-Heise S, Hampe W, Bussche van den H
GMS J MED EDU. 2021;38(6):Doc102.

NAADP: From Discovery to Mechanism
Walseth T, Guse A
FRONT IMMUNOL. 2021;12:703326.

Time-Dependent Image Restoration of Low-SNR Live-Cell Ca2+ Fluorescence Microscopy Data
Woelk L, Kannabiran S, Brock V, Gee C, Lohr C, Guse A, Diercks B, Werner R
INT J MOL SCI. 2021;22:.

Stimulation of Local Cytosolic Calcium Release by Photothermal Heating for Studying Intra- and Intercellular Calcium Waves
Zhu D, Feng L, Feliu N, Guse A, Parak W
ADV MATER. 2021;33(24):e2008261.

Apolipoprotein E4 disrupts the neuroprotective action of sortilin in neuronal lipid metabolism and endocannabinoid signaling
Asaro A, Carlo-Spiewok A, Malik A, Rothe M, Schipke C, Peters O, Heeren J, Willnow T
ALZHEIMERS DEMENT. 2020;16(9):1248-1258.

Synthesis of phosphonoacetate analogues of the second messenger adenosine 5'-diphosphate ribose (ADPR)
Baszczyňski O, Watt J, Rozewitz M, Fliegert R, Guse A, Potter B
RSC ADV. 2020;10(3):1776-1785.

Perspektiven und Probleme von Ärztinnen und Ärzten in Weiterbildung: Welche beruflichen Präferenzen haben Ärztinnen und Ärzte nach sechs Jahren Weiterbildungszeit – welche Arbeitsmodelle streben sie an? Antworten gibt die KarMed-Studie, die regelmäßig Karrieren von Weiterzubildenden vom Berufseinstieg bis zur fachärztlichen Anerkennung untersucht.
Boczor S, Kocalevent R, Selch S, Bussche van den H
Hamb Ärztebl. 2020;74(02):15-17.

Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice
Fischer A, Behrens J, Sass F, Schlein C, Heine M, Pertzborn P, Scheja L, Heeren J
J LIPID RES. 2020;61(11):1377-1389.

Leptin: Is It Thermogenic?
Fischer A, Cannon B, Nedergaard J
ENDOCR REV. 2020;41(2):232–260.

Thermoneutrality-Induced Macrophage Accumulation in Brown Adipose Tissue Does Not Impair the Tissue's Competence for Cold-Induced Thermogenic Recruitment
Fischer A, de Jong J, Sass F, Schlein C, Heeren J, Petrovic N
FRONT ENDOCRINOL. 2020;11:568682.

Does Cyclic ADP-Ribose (cADPR) Activate the Non-selective Cation Channel TRPM2?
Fliegert R, Riekehr W, Guse A
FRONT IMMUNOL. 2020;11:.

Need for cognitive closure, tolerance for ambiguity, and perfectionism in medical school applicants
Gärtner J, Bußenius L, Prediger S, Vogel D, Harendza S
BMC MED EDUC. 2020;20(1):.

Persönlichkeitseigenschaften in der Anästhesiologie: Ergebnisse einer fragebogenbasierten Anforderungsanalyse
Gassner S, Oubaid V, Hampe W, Kubitz J
ANAESTHESIST. 2020;69(11):803-809.

25 Years of Collaboration with A Genius: Deciphering Adenine Nucleotide Ca2+ Mobilizing Second Messengers Together with Professor Barry Potter
Guse A
MOLECULES. 2020;25(18):.

Reservoir Computing for Jurkat T-cell Segmentation in High Resolution Live Cell Ca2+ Fluorescence Microscopy
Hadäghi F, Diercks B, Wolf I, Werner R
Proc IEEE ISBI 2020. 2020;(1):1587-1591.

Contribution of NAADP to Glutamate-Evoked Changes in Ca2+ Homeostasis in Mouse Hippocampal Neurons
Hermann J, Bender M, Schumacher D, Woo M, Shaposhnykov A, Rosenkranz S, Kuryshev V, Meier C, Guse A, Friese M, Freichel M, Tsvilovskyy V
FRONT CELL DEV BIOL. 2020;8:496.

High Metabolic Function and Resilience of NKG2A-Educated NK Cells
Highton A, Diercks B, Möckl F, Martrus G, Sauter J, Schmidt A, Bunders M, Körner C, Guse A, Altfeld M
FRONT IMMUNOL. 2020;11:.

A structural overview of the ion channels of the TRPM family
Huang Y, Fliegert R, Guse A, Lü W, Du J
CELL CALCIUM. 2020;85:.

Impaired Bone Microarchitecture in Patients with Hereditary Hemochromatosis and Skeletal Complications
Jandl N, Rolvien T, Schmidt T, Mussawy H, Nielsen P, Oheim R, Amling M, Barvencik F
CALCIFIED TISSUE INT. 2020;106(5):465-475.

Real-time monitoring of cAMP in brown adipocytes reveals differential compartmentation of β1 and β3-adrenoceptor signalling
Kannabiran S, Gosejacob D, Niemann B, Nikolaev V, Pfeifer A
MOL METAB. 2020;37:100986.

IL22BP Mediates the Anti-Tumor Effects of Lymphotoxin Against Colorectal Tumors in Mice and Humans
Kempski J, Giannou A, Riecken K, Zhao L, Steglich B, Lücke J, Garcia-Perez L, Karstens K, Wöstemeier A, Nawrocki M, Pelczar P, Witkowski M, Nilsson S, Konczalla L, Shiri A, Kempska J, Wahib R, Brockmann L, Huber P, Gnirck A, Turner J, Zazara D, Arck P, Stein A, Simon R, Daubmann A, Meiners J, Perez D, Strowig T, Koni P, Kruglov A, Sauter G, Izbicki J, Guse A, Roesch T, Lohse A, Flavell R, Gagliani N, Huber S
GASTROENTEROLOGY. 2020;159(4):1417-1430.e3.

Burnout is associated with work-family conflict and gratification crisis among German resident physicians
Kocalevent R, Pinnschmidt H, Selch S, Nehls S, Meyer J, Boczor S, Scherer M, van den Bussche H
BMC MED EDUC. 2020;20(1):145.

Therapeutic Targeting of Myeloperoxidase Attenuates NASH in Mice
Koop A, Thiele N, Steins D, Michaëlsson E, Wehmeyer M, Scheja L, Steglich B, Huber S, Schulze zur Wiesch J, Lohse A, Heeren J, Kluwe J
HEPATOL COMMUN. 2020;4(10):1441-1458.

Presentation and evaluation of the teaching concept "ENHANCE" for basic sciences in medical education
Kouz K, Eisenbarth S, Bergholz A, Mohr S
PLOS ONE. 2020;15(9):e0239928.

Drugs Modulating CD4+ T Cells Blood-Brain Barrier Interaction in Alzheimer's Disease
Kubick N, Flournoy P, Enciu A, Manda G, Mickael M
PHARMACEUTICS. 2020;12(9):.

What has single-cell RNA sequencing revealed about microglial neuroimmunology?
Kubick N, Henckell Flournoy P, Klimovich P, Manda G, Mickael M
IMMUN INFLAMM DIS. 2020;8(4):825-839.

Repurposing Zileuton as a Depression Drug Using an AI and In Vitro Approach
Kubick N, Pajares M, Enache I, Manda G, Mickael M
MOLECULES. 2020;25(9):.

Alterations of the bile microbiome in primary sclerosing cholangitis
Liwinski T, Zenouzi R, John C, Ehlken H, Rühlemann M, Bang C, Groth S, Lieb W, Kantowski M, Andersen N, Schachschal G, Karlsen T, Hov J, Rösch T, Lohse A, Heeren J, Franke A, Schramm C
GUT. 2020;69(4):665-672.

The nucleus acts as a ruler tailoring cell responses to spatial constraints
Lomakin A, Cattin C, Cuvelier D, Alraies Z, Molina M, Nader G, Srivastava N, Sáez P, Garcia-Arcos J, Zhitnyak I, Bhargava A, Driscoll M, Welf E, Fiolka R, Petrie R, De Silva N, González-Granado J, Manel N, Lennon-Duménil A, Müller D, Piel M
SCIENCE. 2020;370(6514):.

Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells
Meneses-Salas E, García-Melero A, Kanerva K, Blanco-Muñoz P, Morales-Paytuvi F, Bonjoch J, Casas J, Egert A, Beevi S, Jose J, Llorente-Cortés V, Rye K, Heeren J, Lu A, Pol A, Tebar F, Ikonen E, Grewal T, Enrich C, Rentero C
CELL MOL LIFE SCI. 2020;77(14):2839-2857.

Academic emotions during an interprofessional learning episode in a clinical context: assessing within- and between-variation
Mohr S, Grahn H, Krohne C, Brätz J, Guse A
J INTERPROF CARE. 2020;35(2):248-256.

Development of the Metabolic Syndrome: Study Design and Baseline Data of the Lufthansa Prevention Study (LUPS), A Prospective Observational Cohort Survey.
Müller-Wieland D, Altenburg C, Becher H, Burchard J, Frisch A, Gebhard J, Haas J, Harth V, Heeren J, Hengelbrock J, von Karais M, Knebel B, Kotzka J, Löwe B, Marx N, Pinnschmidt H, Preisser A, Rose M, Sawitzky-Rose B, Scheja L, Terschüren C, Töller M, Vettorazzi E, Wegscheider K
EXP CLIN ENDOCR DIAB. 2020;128(12):777-787.

Inulin Supplementation Disturbs Hepatic Cholesterol and Bile Acid Metabolism Independent from Housing Temperature
Pauly M, Rohde J, John C, Evangelakos I, Koop A, Pertzborn P, Tödter K, Scheja L, Heeren J, Worthmann A
NUTRIENTS. 2020;12(10):.

Publisher Correction: TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer
Perez L, Kempski J, McGee H, Pelzcar P, Agalioti T, Giannou A, Konczalla L, Brockmann L, Wahib R, Xu H, Vesely M, Soukou S, Steglich B, Bedke T, Manthey C, Seiz O, Diercks B, Gnafakis S, Guse A, Perez D, Izbicki J, Gagliani N, Flavell R, Huber S
NAT COMMUN. 2020.

TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer
Perez L, Kempski J, M McGee H, Pelzcar P, Agalioti T, Giannou A, Konczalla L, Brockmann L, Wahib R, Xu H, Vesely M, Soukou S, Steglich B, Bedke T, Manthey C, Seiz O, Diercks B, Gnafakis S, Guse A, Perez D, Izbicki J, Gagliani N, Flavell R, Huber S
NAT COMMUN. 2020;11(1):.

Warum Interprofessionalität unverzichtbar ist
Pfisterer-Heise S
2020. Die Zukunft der Arbeit im Gesundheitswesen. Amelung V (Hrsg.). 1. Aufl. Berlin: Medizinisch Wissenschaftliche Verlagsgesellschaft, 199-214.

A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism
Pradas-Juni M, Hansmeier N, Link J, Schmidt E, Larsen B, Klemm P, Meola N, Topel H, Loureiro R, Dhaouadi I, Kiefer C, Schwarzer R, Khani S, Oliverio M, Awazawa M, Frommolt P, Heeren J, Scheja L, Heine M, Dieterich C, Büning H, Yang L, Cao H, Jesus D, Kulkarni R, Zevnik B, Tröder S, Knippschild U, Edwards P, Lee R, Yamamoto M, Ulitsky I, Fernandez-Rebollo E, Vallim T, Kornfeld J
NAT COMMUN. 2020;11(1):644.

Skeletal deterioration in COL2A1-related spondyloepiphyseal dysplasia occurs prior to osteoarthritis
Rolvien T, Yorgan T, Kornak U, Hermans-Borgmeyer I, Mundlos S, Schmidt T, Niemeier A, Schinke T, Amling M, Oheim R
OSTEOARTHR CARTILAGE. 2020;28(3):334-343.

The P2X7 ion channel is dispensable for energy and metabolic homeostasis of white and brown adipose tissues
Tian T, Heine M, Evangelakos I, Jaeckstein M, Schaltenberg N, Stähler T, Koch-Nolte F, Kumari M, Heeren J
PURINERG SIGNAL. 2020;16(4):529-542.

Digital Health meets Hamburg integrated medical degree program iMED: Concept and introduction of the new interdisciplinary 2nd track Digital Health
Werner R, Henningsen M, Schmitz R, Guse A, Augustin M, Gauer T
GMS J MED EDU. 2020;37(6):Doc61.

Synthesis of Terminal Ribose Analogues of Adenosine 5'-Diphosphate Ribose as Probes for the Transient Receptor Potential Cation Channel TRPM2
Baszczyňski O, Watt J, Rozewitz M, Guse A, Fliegert R, Potter B
J ORG CHEM. 2019;84(10):6143-6157.

Abscisic acid stimulates the release of insulin and of GLP-1 in the rat perfused pancreas and intestine
Booz V, Christiansen C, Kuhre R, Saltiel M, Sociali G, Schaltenberg N, Fischer A, Heeren J, Zocchi E, Holst J, Bruzzone S
DIABETES-METAB RES. 2019;35(2):e3102.

A defect in the peroxisomal biogenesis in germ cells induces a spermatogenic arrest at the round spermatid stage in mice
Brauns A, Heine M, Tödter K, Baumgart-Vogt E, Lüers G, Schumacher U
SCI REP-UK. 2019;9(1):9553.

The relationship between perfectionism and symptoms of depression in medical school applicants
Bußenius L, Harendza S
BMC MED EDUC. 2019;19(1):370.

Author Correction: Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice
de Jong J, Sun W, Pires N, Frontini A, Balaz M, Jespersen N, Feizi A, Petrovic K, Fischer A, Bokhari M, Niemi T, Nuutila P, Cinti S, Nielsen S, Scheele C, Virtanen K, Cannon B, Nedergaard J, Wolfrum C, Petrovic N
NAT METAB. 2019;1(9):927.

High-Resolution Calcium Imaging Method for Local Calcium Signaling
Diercks B, Werner R, Schetelig D, Wolf I, Guse A
2019. Calcium-Binding Proteins of the EF-Hand Superfamily. 1. Aufl. Humana Press, 27-39.

PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles
Fischer A, Albers K, Schlein C, Sass F, Krott L, Schmale H, Gordts P, Scheja L, Heeren J
BBA-MOL BASIS DIS. 2019;1865(6):1592-1603.

No insulating effect of obesity, neither in mice nor in humans
Fischer A, Cannon B, Nedergaard J
AM J PHYSIOL-ENDOC M. 2019;317(5):E952-E953.

The answer to the question "What is the best housing temperature to translate mouse experiments to humans?" is: thermoneutrality
Fischer A, Cannon B, Nedergaard J
MOL METAB. 2019;26:1-3.

Intact innervation is essential for diet-induced recruitment of brown adipose tissue
Fischer A, Schlein C, Cannon B, Heeren J, Nedergaard J
AM J PHYSIOL-ENDOC M. 2019;316(3):E487-E503.

Adenine nucleotides as paracrine mediators and intracellular second messengers in immunity and inflammation
Fliegert R, Heeren J, Koch-Nolte F, Nikolaev V, Lohr C, Meier C, Guse A
BIOCHEM SOC T. 2019;47(1):329-337.

Novel CaM-binding motif in its NudT9H domain contributes to temperature sensitivity of TRPM2
Gattkowski E, Johnsen A, Bauche A, Möckl F, Kulow F, Garcia Alai M, Rutherford T, Fliegert R, Tidow H
BBA-MOL CELL RES. 2019;1866(7):1162-1170.

Liver infiltrating T cells regulate bile acid metabolism in experimental cholangitis
Glaser F, John C, Engel B, Höh B, Weidemann S, Dieckhoff J, Stein S, Becker N, Casar C, Amrei Schuran F, Wieschendorf B, Preti M, Jessen F, Franke A, Carambia A, Lohse A, Ittrich H, Herkel J, Heeren J, Schramm C, Schwinge D
J HEPATOL. 2019;71(4):783-792.

Biochemie hoch2: und Molekularbiologie
Hampe W, Fluhrer R, Kouz K, Unterleitner C, Averbeck B, Dankwardt A, Duszenko M, Eberharter A, Harter C, Höppner S, Kindler S, Kreienkamp H, Korber P, Neumann S, Nielsen P, Salat D, Schling P, Wild-Bode C
2019.

Correction: Culturing and patch clamping of Jurkat T cells and neurons on Al2O3 coated nanowire arrays of altered morphology
Harberts J, Zierold R, Fendler C, Koitmäe A, Bayat P, Fernandez-Cuesta I, Loers G, Diercks B, Fliegert R, Guse A, Ronning C, Otnes G, Borgström M, Blick R
RSC ADV. 2019;9(24):13614.

Culturing and patch clamping of Jurkat T cells and neurons on Al2O3 coated nanowire arrays of altered morphology
Harberts J, Zierold R, Fendler C, Koitmäe A, Bayat P, Fernandez-Cuesta I, Loers G, Diercks B, Fliegert R, Guse A, Ronning C, Otnes G, Borgström M, Blick R
RSC ADV. 2019;9(20):11194-11201.

Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export
Heybrock S, Kanerva K, Meng Y, Ing C, Liang A, Xiong Z, Weng X, Ah Kim Y, Collins R, Trimble W, Pomès R, Privé G, Annaert W, Schwake M, Heeren J, Lüllmann-Rauch R, Grinstein S, Ikonen E, Saftig P, Neculai D
NAT COMMUN. 2019;10(1):3521.

Thyroid-Hormone-Induced Browning of White Adipose Tissue Does Not Contribute to Thermogenesis and Glucose Consumption
Johann K, Cremer A, Fischer A, Heine M, Pensado E, Resch J, Nock S, Virtue S, Harder L, Oelkrug R, Astiz M, Brabant G, Warner A, Vidal-Puig A, Oster H, Boelen A, López M, Heeren J, Dalley J, Backes H, Mittag J
CELL REP. 2019;27(11):3385-3400.e3.

P2X7-mediated ATP secretion is accompanied by depletion of cytosolic ATP
Johnsen B, Kaschubowski K, Nader S, Schneider E, Nicola J, Fliegert R, Wolf I, Guse A, Nikolaev V, Koch-Nolte F, Haag F
PURINERG SIGNAL. 2019;15(2):155-166.

Exploring sociodemographic subgroup differences in multiple mini-interview (MMI) performance based on MMI station type and the implications for the predictive fairness of the Hamburg MMI
Knorr M, Meyer H, Sehner S, Hampe W, Zimmermann S
BMC MED EDUC. 2019;19(1):243.

Scanning transmission X-ray microscopy with efficient X-ray fluorescence detection (STXM-XRF) for biomedical applications in the soft and tender energy range
Lühl L, Andrianov K, Dierks H, Haidl A, Dehlinger A, Heine M, Heeren J, Nisius T, Wilhein T, Kanngießer B
J SYNCHROTRON RADIAT. 2019;26(Pt 2):430-438.

Glucocorticoid-Induced Obesity Develops Independently of UCP1
Luijten I, Brooks K, Boulet N, Shabalina I, Jaiprakash A, Carlsson B, Fischer A, Cannon B, Nedergaard J
CELL REP. 2019;27(6):1686-1698.e5.

Selection and academic success of medical students in Hamburg, Germany
Meyer H, Zimmermann S, Hissbach J, Klusmann D, Hampe W
BMC MED EDUC. 2019;19(1):23.

Anaesthesiology students' Non-Technical skills: development and evaluation of a behavioural marker system for students (AS-NTS)
Moll-Khosrawi P, Kamphausen A, Hampe W, Schulte-Uentrop L, Zimmermann S, Kubitz J
BMC MED EDUC. 2019;19(1):205.

Full focus on calcium
Parys J, Guse A
SCI SIGNAL. 2019;12(599):.

Synergistic Effects of DHA and Sucrose on Body Weight Gain in PUFA-Deficient Elovl2 -/- Mice
Pauter A, Fischer A, Bengtsson T, Asadi A, Talamonti E, Jacobsson A
NUTRIENTS. 2019;11(4):.

Longitudinale Untersuchung der Berufsverlaufszufriedenheit von Ärztinnen und Ärzten in der Facharztweiterbildung
Pawlik J, Lemmer G, Selch S, Nehls S, Meyer J, Boczor S, Scherer M, Bussche van den H, Kocalevent R
Z EVIDENZ FORTBILD Q. 2019;2019(147-148):103-109.

The Hamburg integrated medical degree program iMED
Rheingans A, Soulos A, Mohr S, Meyer J, Guse A
GMS J MED EDU. 2019;36(5):Doc52.

The endocrine function of adipose tissues in health and cardiometabolic disease
Scheja L, Heeren J
NAT REV ENDOCRINOL. 2019;15(9):507-524.

Human Fetal TNF-α-Cytokine-Producing CD4 Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life
Schreurs R, Baumdick M, Sagebiel A, Kaufmann M, Mokry M, Klarenbeek P, Schaltenberg N, Steinert F, van Rijn J, Drewniak A, The S, Bakx R, Derikx J, de Vries N, Corpeleijn W, Pals S, Gagliani N, Friese M, Middendorp S, Nieuwenhuis E, Reinshagen K, Geijtenbeek T, van Goudoever J, Bunders M
IMMUNITY. 2019;50(2):462-476.e8.

Dissecting hiPSC-CM pacemaker function in a cardiac organoid model
Schulze M, Lemoine M, Fischer A, Scherschel K, David R, Riecken K, Hansen A, Eschenhagen T, Ulmer B
BIOMATERIALS. 2019;206:133-145.

Wie ist die Nachwuchssituation in der Fachrichtung Kinder- und Jugendmedizin einzuschätzen? – Ergebnisse der KarMed-Längsschnittstudie
Selch S, Boczor S, Nehls S, Kocalevent R, Scherer M, Bussche van den H
Kinder- und Jugendarzt. 2019;68(11):686-694.

Dietary Habits and Intestinal Immunity: From Food Intake to CD4(+) T-H Cells
Siracusa F, Schaltenberg N, Villablanca E, Huber S, Gagliani N
FRONT IMMUNOL. 2019;9:3177.

NAD binding by human CD38 analyzed by Trp189 fluorescence
Wolters V, Rosche A, Bauche A, Kulow F, Harneit A, Fliegert R, Guse A
BBA-MOL CELL RES. 2019;1866(7):1189-1196.

Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression
Worthmann A, Schlein C, Berbée J, Rensen P, Heeren J, Bartelt A
NUTRIENTS. 2019;11(2):.

Lrp1 in osteoblasts controls osteoclast activity and protects against osteoporosis by limiting PDGF-RANKL signaling
Bartelt A, Behler-Janbeck F, Beil F, Koehne T, Müller B, Schmidt T, Heine M, Ochs L, Yilmaz T, Dietrich M, Tuckermann J, Amling M, Herz J, Schinke T, Heeren J, Niemeier A
BONE RES. 2018;6:4.

Altered hepatic glucose homeostasis in AnxA6-KO mice fed a high-fat diet
Cairns R, Fischer A, Blanco-Munoz P, Alvarez-Guaita A, Meneses-Salas E, Egert A, Buechler C, Hoy A, Heeren J, Enrich C, Rentero C, Grewal T
PLOS ONE. 2018;13(8):e0201310.

The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity
Christoffersen C, Federspiel C, Borup A, Christensen P, Madsen A, Heine M, Nielsen C, Kjaer A, Holst B, Heeren J, Nielsen L
CELL REP. 2018;22(1):175-188.

ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.
Diercks B, Werner R, Weidemüller P, Czarniak F, Hernandez L, Lehmann C, Rosche A, Krüger A, Kaufmann U, Vaeth M, Failla A, Zobiak B, Kandil F, Schetelig D, Ruthenbeck A, Meier C, Lodygin D, Flügel A, Ren D, Wolf I, Feske S, Guse A
SCI SIGNAL. 2018; 11(561):eaat0358.

The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins
Fischer A, Albers K, Krott L, Hoffzimmer B, Heine M, Schmale H, Scheja L, Gordts P, Heeren J
MOL METAB. 2018;16:88-99.

Optimal housing temperatures for mice to mimic the thermal environment of humans: An experimental study
Fischer A, Cannon B, Nedergaard J
MOL METAB. 2018;7:161-170.

TRPM2 activation: Paradigm shifted?
Fliegert R, Hölzer H, Guse A
CELL CALCIUM. 2018;S0143-4160:.

Fragebogenbasierte Anforderungsanalyse für das Berufsbild des Anästhesiologen
Gassner S, Oubaid V, Hampe W, Zöllner C, Kubitz J
ANASTH INTENSIVMED. 2018;59:114-120.

Pancreatic iron and fat, early indicators of impaired glucose metabolism?
Grosse R, Berliner C, Hainmann I, Weyhmiller M, Fung E, Schönnagel B, Yamamura J, Nielsen P, Fischer R
2018. ABSTRACT BOOK. .

Integration of nicotinic acid adenine dinucleotide phosphate (NAADP)-dependent calcium signalling
Guse A, Diercks B
J PHYSIOL-LONDON. 2018;596(14):2735-2743.

Modellstudiengänge in der Medizin
Guse A, Kuhlmey A
BUNDESGESUNDHEITSBLA. 2018;61(2):132-140.

Brown adipose tissue and lipid metabolism
Heeren J, Scheja L
CURR OPIN LIPIDOL. 2018;29(3):180-185.

Lipolysis Triggers a Systemic Insulin Response Essential for Efficient Energy Replenishment of Activated Brown Adipose Tissue in Mice
Heine M, Fischer A, Schlein C, Jung C, Straub L, Gottschling K, Mangels N, Yuan Y, Nilsson S, Liebscher G, Chen O, Schreiber R, Zechner R, Scheja L, Heeren J
CELL METAB. 2018;28(4):644-655.e4.

Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells
Jayson C, Arlt H, Fischer A, Lai Z, Farese R, Walther T
MOL BIOL CELL. 2018;29(17):2045-2054.

Validity evidence for the Hamburg multiple mini-interview
Knorr M, Schwibbe A, Ehrhardt M, Lackamp J, Zimmermann S, Hampe W
BMC MED EDUC. 2018;18(1):106.

Medizinische Ausbildung in Bewegung
Koch-Gromus U, Guse A, van den Bussche H
BUNDESGESUNDHEITSBLA. 2018;61(2):129-131.

Molecular Evolution and Functional Divergence of the IgLON Family
Kubick N, Brösamle D, Mickael M
EVOL BIOINFORM. 2018;14:1176934318775081.

Regulation of immunometabolism in adipose tissue
Kumari M, Heeren J, Scheja L
SEMIN IMMUNOPATHOL. 2018;40(2):189-202.

FoxO transcription factors are required for hepatic HDL-cholesterol clearance
Lee S, Heine M, Schlein C, Ramakrishnan R, Liu J, Belnavis G, Haimi I, Fischer A, Ginsberg H, Heeren J, Rinninger F, Haeusler R
J CLIN INVEST. 2018;128(4):1615-1626.

Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans
Oldoni F, van Capelleveen J, Dalila N, Wolters J, Heeren J, Sinke R, Hui D, Dallinga-Thie G, Frikke-Schmidt R, Hovingh K, van de Sluis B, Tybjærg-Hansen A, Kuivenhoven J
ARTERIOSCL THROM VAS. 2018;38(7):1440-1453.

Membrane-Permeable Octanoyloxybenzyl-Masked cNMPs As Novel Tools for Non-Invasive Cell Assays.
Ruthenbeck A, Marangoni E, Diercks B, Krüger A, Froese A, Bork N, Nikolaev V, Guse A, Meier C
MOLECULES. 2018;23(11):E2960.

Introduction to the special issue on dietary control of immunometabolism
Scheja L, Heeren J
SEMIN IMMUNOPATHOL. 2018;40(2):141-144.

LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat
Schmidt E, Dhaouadi I, Gaziano I, Oliverio M, Klemm P, Awazawa M, Mitterer G, Fernandez-Rebollo E, Pradas-Juni M, Wagner W, Hammerschmidt P, Loureiro R, Kiefer C, Hansmeier N, Khani S, Bergami M, Heine M, Ntini E, Frommolt P, Zentis P, Ørom U, Heeren J, Blüher M, Bilban M, Kornfeld J
NAT COMMUN. 2018;9(1):3622.

Medizinstudierendenauswahl in Deutschland: Messung kognitiver Fähigkeiten und psychosozialer Kompetenzen
Schwibbe A, Lackamp J, Knorr M, Hissbach J, Kadmon M, Hampe W
BUNDESGESUNDHEITSBLA. 2018;61(2):178-186.

Dietary protein restriction reduces circulating VLDL triglyceride levels via CREBH-APOA5-dependent and -independent mechanisms
Treviño-Villarreal J, Reynolds J, Bartelt A, Langston P, MacArthur M, Arduini A, Tosti V, Veronese N, Bertozzi B, Brace L, Mejia P, Trocha K, Kajitani G, Longchamp A, Harputlugil E, Gathungu R, Bird S, Bullock A, Figenshau R, Andriole G, Thompson A, Heeren J, Ozaki C, Kristal B, Fontana L, Mitchell J
JCI INSIGHT. 2018;3(21):.

Comparison of Fatty Acid and Gene Profiles in Skeletal Muscle in Normal and Obese C57BL/6J Mice before and after Blunt Muscle Injury
Werner J, Tödter K, Xu P, Lockhart L, Jähnert M, Gottmann P, Schürmann A, Scheja L, Wabitsch M, Knippschild U
FRONT PHYSIOL. 2018;9:19.

Assessment of Uptake and Biodistribution of Radiolabeled Cholesterol in Mice Using Gavaged Recombinant Triglyceride-rich Lipoprotein Particles (rTRL)
Worthmann A, John C, Heeren J
BIO-PROTOCOL. 2018;8(13):e2916.

Small Molecule Antagonists of NAADP-Induced Ca Release in T-Lymphocytes Suggest Potential Therapeutic Agents for Autoimmune Disease
Zhang B, Watt J, Cordiglieri C, Dammermann W, Mahon M, Flügel A, Guse A, Potter B
SCI REP-UK. 2018;8(1):16775.

Lesekompetenz, curriculare Veränderungen und Übergang in die Berufsausbildung: Untersuchungen mit Daten des Nationalen Bildungspanels
Zimmermann S
2018.

Angleichung von Schulnoten für die Studierendenauswahl
Zimmermann S, Klusmann D, Hampe W
Z Hochschulentwicklung. 2018;13(3):179-197.

AMPK Prevents Palmitic Acid-Induced Apoptosis and Lipid Accumulation in Cardiomyocytes
Adrian L, Lenski M, Tödter K, Heeren J, Böhm M, Laufs U
LIPIDS. 2017;52(9):737-750.

Systematic Analysis of Jurkat T-Cell Deformation in Fluorescence Microscopy Data
Antoni S, Ismail O, Schetelig D, Diercks B, Werner R, Wolf I, Guse A, Schlaefer A
2017. Bildverarbeitung für die Medizin 2017. Maier-Hain K, Deserno T, Handels H, Thomas T (Hrsg.). 1. Aufl. Springer, 275-280.

Differential effects of Calca-derived peptides in male mice with diet-induced obesity
Bartelt A, Jeschke A, Müller B, Gaziano I, Morales M, Yorgan T, Heckt T, Heine M, Gagel R, Emeson R, Amling M, Niemeier A, Heeren J, Schinke T, Keller J
PLOS ONE. 2017;12(6):e0180547.

Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport
Bartelt A, John C, Schaltenberg N, Berbée J, Worthmann A, Cherradi M, Schlein C, Piepenburg J, Boon M, Rinninger F, Heine M, Toedter K, Niemeier A, Nilsson S, Fischer M, Wijers S, van Marken Lichtenbelt W, Scheja L, Rensen P, Heeren J
NAT COMMUN. 2017;8:Art. 15010.

Quantification of Bone Fatty Acid Metabolism and Its Regulation by Adipocyte Lipoprotein Lipase
Bartelt A, Koehne T, Tödter K, Reimer R, Müller B, Behler-Janbeck F, Heeren J, Scheja L, Niemeier A
INT J MOL SCI. 2017;18(6):1264.

Ultra-fast cell counters based on microtubular waveguides
Bausch C, Heyn C, Hansen W, Wolf I, Diercks B, Guse A, Blick R
SCI REP-UK. 2017;7(41584):.

Next-Generation optical imaging with short-wave infrared quantum dots
Bruns O, Bischof T, Harris D, Franke D, Shi Y, Riedemann L, Bartelt A, Jaworski F, Carr J, Rowlands C, Wilson M, Chen O, Wei H, Hwang G, Montana D, Coropceanu I, Achorn O, Kloepper J, Heeren J, So P, Fukumura D, Jensen K, Jain R, Bawendi M
NAT BIOMED ENG. 2017;1(4):UNSP 0056.

Metabolic Circuit Involving Free Fatty Acids, microRNA 122, and Triglyceride Synthesis in Liver and Muscle Tissues
Chai C, Rivkin M, Berkovits L, Simerzin A, Zorde-Khvalevsky E, Rosenberg N, Klein S, Yaish D, Durst R, Shpitzen S, Udi S, Tam J, Heeren J, Worthmann A, Schramm C, Kluwe J, Ravid R, Hornstein E, Giladi H, Galun E
GASTROENTEROLOGY. 2017;153(5):1404-1415.

Mag-Fluo4 in T cells: Imaging of intra-organelle free Ca(2+) concentrations
Diercks B, Fliegert R, Guse A
BBA-MOL CELL RES. 2017;1864(6):977-986.

Leptin-deficient mice are not hypothermic, they are anapyrexic
Fischer A, Cannon B, Nedergaard J
MOL METAB. 2017;6(2):173.

UCP1 inhibition in Cidea-overexpressing mice is physiologically counteracted by brown adipose tissue hyperrecruitment
Fischer A, Shabalina I, Mattsson C, Abreu-Vieira G, Cannon B, Nedergaard J, Petrovic N
AM J PHYSIOL-ENDOC M. 2017;312(1):E72-E87.

2'-Deoxyadenosine 5'-diphosphoribose is an endogenous TRPM2 superagonist
Fliegert R, Bauche A, Wolf Pérez A, Watt J, Rozewitz M, Winzer R, Janus M, Gu F, Rosche A, Harneit A, Flato M, Moreau C, Kirchberger T, Wolters V, Potter B, Guse A
NAT CHEM BIOL. 2017;13(9):1036-1044.

Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349
Fliegert R, Watt J, Schöbel A, Rozewitz M, Moreau C, Kirchberger T, Thomas M, Sick W, Araujo A, Harneit A, Potter B, Guse A
BIOCHEM J. 2017;474(13):2159-2175.

Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38+ tumors in mouse models in vivo
Fumey W, Koenigsdorf J, Kunick V, Menzel S, Schütze K, Unger M, Schriewer L, Haag F, Adam G, Oberle A, Binder M, Fliegert R, Guse A, Zhao Y, Cheung Lee H, Malavasi F, Goldbaum F, van Hegelsom R, Stortelers C, Bannas P, Koch-Nolte F
SCI REP-UK. 2017;7(1):14289.

Die Rolle des Patienten in der vernetzten Gesundheitsversorgung
Groene O, Groene O
2017. Vernetzte Versorgung. 109-127.

Impact of non-transferrin-bound iron (NTBI) in comparison to serum ferritin on outcome after allogeneic stem cell transplantation (ASCT)
Hilken A, Langebrake C, Wolschke C, Kersten J, Rohde H, Nielsen P, Kröger N
ANN HEMATOL. 2017;96(8):1379-1388.

Cold-Induced Brown Adipose Tissue Activity Alters Plasma Fatty Acids and Improves Glucose Metabolism in Men
Iwen K, Backhaus J, Cassens M, Waltl M, Hedesan O, Merkel M, Heeren J, Sina C, Rademacher L, Windjäger A, Haug A, Kiefer F, Lehnert H, Schmid S
J CLIN ENDOCR METAB. 2017;102(11):4226-4234.

Histological Analysis
Johansson C, Röser K, Jimbo R, Hammarström Johansson P, Larsson L, Östberg A
2017. Comprehensive Biomaterials II. Ducheyne P, Healy K, Hutmacher D, Grainger D, Kirkpatrick C (Hrsg.). 2. Aufl. Oxford: 335-363.

Quantitative and qualitative estimation of atherosclerotic plaque burden in vivo at 7T MRI using Gadospin F in comparison to en face preparation evaluated in ApoE KO mice
Jung C, Christiansen S, Kaul M, Koziolek E, Reimer R, Heeren J, Adam G, Heine M, Ittrich H
PLOS ONE. 2017;12(8):e0180407.

An extended fatty liver index to predict non-alcoholic fatty liver disease
Kantartzis K, Rettig I, Staiger H, Machann J, Schick F, Scheja L, Gastaldelli A, Bugianesi E, Peter A, Schulze M, Fritsche A, Häring H, Stefan N
DIABETES METAB. 2017;43(3):229-239.

TH17 Cell and Epithelial Cell Crosstalk during Inflammatory Bowel Disease and Carcinogenesis
Kempski J, Brockmann L, Gagliani N, Huber S
FRONT IMMUNOL. 2017;8:1373.

Disruption of the vacuolar-type H-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes
Kissing S, Rudnik S, Damme M, Lüllmann-Rauch R, Ichihara A, Kornak U, Eskelinen E, Jabs S, Heeren J, De Brabander J, Haas A, Saftig P
AUTOPHAGY. 2017;13(4):670-685.

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
Krasemann S, Madore C, Cialic R, Baufeld C, Calcagno N, El Fatimy R, Beckers L, O'Loughlin E, Xu Y, Fanek Z, Greco D, Smith S, Tweet G, Humulock Z, Zrzavy T, Conde-Sanroman P, Gacias M, Weng Z, Chen H, Tjon E, Mazaheri F, Hartmann K, Madi A, Ulrich J, Glatzel M, Worthmann A, Heeren J, Budnik B, Lemere C, Ikezu T, Heppner F, Litvak V, Holtzman D, Lassmann H, Weiner H, Ochando J, Haass C, Butovsky O
IMMUNITY. 2017;47(3):566-581.e9.

Identification of a plasma miRNA biomarker signature for allergic asthma: A translational approach
Milger K, Götschke J, Krause L, Nathan P, Alessandrini F, Tufman A, Fischer R, Bartel S, Theis F, Behr J, Dehmel S, Mueller N, Kneidinger N, Krauss-Etschmann S
ALLERGY. 2017;72(12):1962-1971.

Retard-Eisensulfat kompensiert den Blutverlust
Nielsen P, Kongi R, Fischer R
MMW Fortschr Med. 2017;159(9):71-71.

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue
Schugar R, Shih D, Warrier M, Helsley R, Burrows A, Ferguson D, Brown A, Gromovsky A, Heine M, Chatterjee A, Li L, Li X, Wang Z, Willard B, Meng Y, Kim H, Che N, Pan C, Lee R, Crooke R, Graham M, Morton R, Langefeld C, Das S, Rudel L, Zein N, McCullough A, Dasarathy S, Tang W, Erokwu B, Flask C, Laakso M, Civelek M, Naga Prasad S, Heeren J, Lusis A, Hazen S, Brown J
CELL REP. 2017;19(12):2451-2461.

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue (vol 19, pg 2451, 2017)
Schugar R, Shih D, Warrier M, Helsley R, Burrows A, Ferguson D, Brown A, Gromovsky A, Heine M, Chatterjee A, Li L, Li X, Wang Z, Willard B, Meng Y, Kim H, Che N, Pan C, Lee R, Crooke R, Graham M, Morton R, Langefeld C, Das S, Rudel L, Zein N, McCullough A, Dasarathy S, Tang W, Erokwu B, Flask C, Laakso M, Civelek M, Naga Prasad S, Heeren J, Lusis A, Hazen S, Brown J
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MRI-based quantitative susceptibility mapping (QSM) and R2* mapping of liver iron overload Comparison with SQUID-based biomagnetic liver susceptometry
Sharma S, Fischer R, Schoennagel B, Nielsen P, Kooijman H, Yamamura J, Adam G, Bannas P, Hernando D, Reeder S
MAGN RESON MED. 2017;78(1):264-270.

Impairment of systemic DHA synthesis affects macrophage plasticity and polarization: implications for DHA supplementation during inflammation
Talamonti E, Pauter A, Asadi A, Fischer A, Chiurchiù V, Jacobsson A
CELL MOL LIFE SCI. 2017;74(15):2815-2826.

Exceedingly small iron oxide nanoparticles as positive MRI contrast agents
Wei H, Bruns O, Kaul M, Hansen E, Barch M, Wiśniowska A, Chen O, Chen Y, Li N, Okada S, Cordero J, Heine M, Farrar C, Montana D, Adam G, Ittrich H, Jasanoff A, Nielsen P, Bawendi M
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Ca2+ Microdomains in T-Lymphocytes
Wolf I, Guse A
FRONT ONCOL. 2017.

Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis
Worthmann A, John C, Rühlemann M, Baguhl M, Heinsen F, Schaltenberg N, Heine M, Schlein C, Evangelakos I, Mineo C, Fischer M, Dandri M, Kremoser C, Scheja L, Franke A, Shaul P, Heeren J
NAT MED. 2017;23(7):839-849.

Correcting the predictive validity of a selection test for the effect of indirect range restriction
Zimmermann S, Klusmann D, Hampe W
BMC MED EDUC. 2017;17:246.

Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity
Chen Y, Buyel J, Hanssen M, Siegel F, Pan R, Naumann J, Schell M, van der Lans A, Schlein C, Froehlich H, Heeren J, Virtanen K, van Marken Lichtenbelt W, Pfeifer A
NAT COMMUN. 2016;7:11420.

Exploring the value and role of integrated supportive science courses in the reformed medical curriculum iMED: a mixed methods study
Eisenbarth S, Tilling T, Lueerss E, Meyer J, Sehner S, Guse A, Guse J
BMC MED EDUC. 2016;16:132.

Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo
Eldridge S, Nalesso G, Ismail H, Vicente-Greco K, Kabouridis P, Ramachandran M, Niemeier A, Herz J, Pitzalis C, Perretti M, Dell'Accio F
ANN RHEUM DIS. 2016;75(6):1228-35.

In vivo degeneration and the fate of inorganic nanoparticles
Feliu N, Docter D, Heine M, Del Pino P, Ashraf S, Kolosnjaj-Tabi J, Macchiarini P, Nielsen P, Alloyeau D, Gazeau F, Stauber R, Parak W
CHEM SENSES. 2016;45(9):2440-57.

No insulating effect of obesity
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Reply to letter to the editor: at thermoneutrality, neither the lean nor the obese freeze
Fischer A, Csikasz R, von Essen G, Cannon B, Nedergaard J
AM J PHYSIOL-ENDOC M. 2016;311(3):E639.

Leptin Raises Defended Body Temperature without Activating Thermogenesis
Fischer A, Hoefig C, Abreu-Vieira G, de Jong J, Petrovic N, Mittag J, Cannon B, Nedergaard J
CELL REP. 2016;14(7):1621-31.

Novel Mouse Models of Methylmalonic Aciduria Recapitulate Phenotypic Traits with a Genetic Dosage Effect
Forny P, Schumann A, Mustedanagic M, Mathis D, Wulf M, Naegele N, Langhans C, Zhakupova A, Heeren J, Scheja L, Fingerhut R, Peters H, Hornemann T, Thony B, Koelker S, Burda P, Froese D, Devuyst O, Baumgartner M
J BIOL CHEM. 2016;291(39):20563-73.

Health Literacy: Literature review for the German National Health Literacy Action Plan
Groene O
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Ca(2+) microdomains, NAADP and type 1 ryanodine receptor in cell activation.
Guse A, Wolf I
BBA-MOL CELL RES. 2016;1863(6):1379-1384.

Effects of Mentoring Speed Dating as an Innovative Matching Tool in Undergraduate Medical Education: A Mixed Methods Study
Guse J, Schweigert E, Kulms G, Heinen I, Martens C, Guse A
PLOS ONE. 2016;11(2):e0147444.

Investigation of the anti-obesity effect of Pueraria montana var. lobata
Houriet J, Buhlmann E, Rudigier C, Kiehlmann E, Radtke J, Heeren J, Friedemann T, Schröder S, Wolfrum C, Wolfender J
PLANTA MED. 2016;81(S 01):S1-S381.

Quantitative Activity Measurements of Brown Adipose Tissue at 7 T Magnetic Resonance Imaging After Application of Triglyceride-Rich Lipoprotein 59Fe-Superparamagnetic Iron Oxide Nanoparticle: Intravenous Versus Intraperitoneal Approach
Jung C, Heine M, Freund B, Reimer R, Koziolek E, Kaul M, Kording F, Schumacher U, Weller H, Nielsen P, Adam G, Heeren J, Ittrich H
INVEST RADIOL. 2016;51(3):194-202.

Acquisition of dental skills in preclinical technique courses: influence of spatial and manual abilities
Kothe C, Schwibbe A, Hampe W, Konradt U
ADV HEALTH SCI EDUC. 2016;21(4):841-57.

Attenuated viral hepatitis in Trem1-/- mice is associated with reduced inflammatory activity of neutrophils
Kozik J, Trautmann T, Carambia A, Preti M, Lütgehetmann M, Krech T, Wiegard C, Heeren J, Herkel J
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Endocannabinoid regulation in white and brown adipose tissue following thermogenic activation
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Wirksamkeit eines Eisen-Retardpräparates bei Eisenmangelanämie
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MMW Fortschr Med. 2016;158(Suppl 6):17-23.

Dicer1-miR-328-Bace1 signalling controls brown adipose tissue differentiation and function
Oliverio M, Schmidt E, Mauer J, Baitzel C, Hansmeier N, Khani S, Konieczka S, Pradas-Juni M, Brodesser S, Van T, Bartsch D, Brönneke H, Heine M, Hilpert H, Tarcitano E, Garinis G, Frommolt P, Heeren J, Mori M, Brüning J, Kornfeld J
NAT CELL BIOL. 2016;18(3):328-36.

Resveratrol and Lifespan in Model Organisms
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CURR MED CHEM. 2016;23(41):4641-4682.

Magnetic Particle / Magnetic Resonance Imaging: In-Vitro MPI-Guided Real Time Catheter Tracking and 4D Angioplasty Using a Road Map and Blood Pool Tracer Approach
Salamon J, Hofmann M, Jung C, Kaul M, Werner F, Them K, Reimer R, Nielsen P, Vom Scheidt A, Adam G, Knopp T, Ittrich H
PLOS ONE. 2016;11(6):e0156899.

Metabolic interplay between white, beige, brown adipocytes and the liver
Scheja L, Heeren J
J HEPATOL. 2016;64(5):1176-86.

Insulin Regulates Hepatic Triglyceride Secretion and Lipid Content via Signaling in the Brain
Scherer T, Lindtner C, O'Hare J, Hackl M, Zielinski E, Freudenthaler A, Baumgartner-Parzer S, Tödter K, Heeren J, Krššák M, Scheja L, Fürnsinn C, Buettner C
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Implications of thermogenic adipose tissues for metabolic health
Schlein C, Heeren J
BEST PRACT RES CL EN. 2016;30(4):487-496.

FGF21 Lowers Plasma Triglycerides by Accelerating Lipoprotein Catabolism in White and Brown Adipose Tissues
Schlein C, Talukdar S, Heine M, Fischer A, Krott L, Nilsson S, Brenner M, Heeren J, Scheja L
CELL METAB. 2016;23(3):441-53.

Peak Filling Rates Assessed by CMR Imaging Indicate Diastolic Dysfunction From Myocardial Iron Toxicity
Schoennagel B, Fischer R, Grosse R, Berliner C, Wehbe M, Kurio G, Lund G, Wang Z, Graessner J, Adam G, Yamamura J
JACC-CARDIOVASC IMAG. 2016;9(11):1353-1354.

Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis
Schröder T, Kucharczyk D, Bär F, Pagel R, Derer S, Jendrek S, Sünderhauf A, Brethack A, Hirose M, Möller S, Künstner A, Bischof J, Weyers I, Heeren J, Koczan D, Schmid S, Divanovic S, Giles D, Adamski J, Fellermann K, Lehnert H, Köhl J, Ibrahim S, Sina C
CELL METAB. 2016;5(4):283-95.

Utilizing immunoaffinity chromatography (IAC) cross-reactivity in GC-MS/MS exemplified at the measurement of prostaglandin E1 in human plasma using prostaglandin E2-specific IAC columns
Tsikas D, Suchy M, Tödter K, Heeren J, Scheja L
J CHROMATOGR B. 2016;1021:101-7.

Basic Principles of Science in Medical Education - Development and Implementation of a Two Week Introductory Track
Vonneilich N, Dubben H, Kriston L, Guse A, von dem Knesebeck O
Creat Educ. 2016;7(6):831-837.

Entwicklung einer computerbasierten Schwierigkeitsabschätzung von Leseverstehensaufgaben
Zimmermann S
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Are Exam Questions Known in Advance? Using Local Dependence to Detect Cheating
Zimmermann S, Klusmann D, Hampe W
PLOS ONE. 2016;11(12):e0167545.

Cidea improves the metabolic profile through expansion of adipose tissue
Abreu-Vieira G, Fischer A, Mattsson C, de Jong J, Shabalina I, Rydén M, Laurencikiene J, Arner P, Cannon B, Nedergaard J, Petrovic N
NAT COMMUN. 2015;6:Art. 7433.

The distribution and degradation of radiolabeled superparamagnetic iron oxide nanoparticles and quantum dots in mice
Bargheer D, Giemsa A, Freund B, Heine M, Waurisch C, Stachowski G, Hickey S, Eychmüller A, Heeren J, Nielsen P
BEILSTEIN J NANOTECH. 2015;6:111-23.

The fate of a designed protein corona on nanoparticles in vitro and in vivo
Bargheer D, Nielsen J, Gébel G, Heine M, Salmen S, Stauber R, Weller H, Heeren J, Nielsen P
BEILSTEIN J NANOTECH. 2015;6:36-46.

Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice
Baumeier C, Kaiser D, Heeren J, Scheja L, John C, Weise C, Eravci M, Lagerpusch M, Schulze G, Joost H, Schwenk R, Schürmann A
Biochim Biophys Acta. 2015;1851(5):566-76.

Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
Berbée J, Boon M, Khedoe P, Bartelt A, Schlein C, Worthmann A, Kooijman S, Hoeke G, Mol I, John C, Jung C, Vazirpanah N, Brouwers L, Gordts P, Esko J, Hiemstra P, Havekes L, Scheja L, Heeren J, Rensen P
NAT COMMUN. 2015;6:6356.

Bestimmung des hypophysären Eisengehaltes mittels Multi-Echo-MRT-R2 Messungen
Berliner C, Brehmer M, Fischer R, Grosse R, Karul M, Keller S, Schönnagel B, Wang J, Adam G, Yamamura J
ROFO-FORTSCHR RONTG. 2015;187(S 01):WISS105_1.

Nanoparticle-based autoantigen delivery to Treg-inducing liver sinusoidal endothelial cells enables control of autoimmunity in mice
Carambia A, Freund B, Schwinge D, Bruns O, Salmen S, Ittrich H, Reimer R, Heine M, Huber S, Waurisch C, Eychmüller A, Wraith D, Korn T, Nielsen P, Weller H, Schramm C, Lüth S, Lohse A, Heeren J, Herkel J
J HEPATOL. 2015;62(6):1349-1356.

ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure
Dijk W, Heine M, Vergnes L, Boon M, Schaart G, Hesselink M, Reue K, van Marken Lichtenbelt W, Olivecrona G, Rensen P, Heeren J, Kersten S
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Calcium mobilizing second messengers derived from NAD
Guse A
BBA-PROTEINS PROTEOM. 2015;1854(9):1132-1137.

Annual conference of the GMA, Hamburg
Hampe W, Kuhnigk O
GMS J MED EDU. 2015;32(2):Doc16.

Prevalence of non-alcoholic fatty liver disease in four different weight related patient Groups: association with small bowel length and risk factors
Hillenbrand A, Kiebler B, Schwab C, Scheja L, Xu P, Henne-Bruns D, Wolf A, Knippschild U
BMC RES NOTES. 2015;8:290.

Stimulation of soluble guanylyl cyclase protects against obesity by recruiting brown adipose tissue
Hoffmann L, Etzrodt J, Willkomm L, Sanyal A, Scheja L, Fischer A, Stasch J, Bloch W, Friebe A, Heeren J, Pfeifer A
NAT COMMUN. 2015;6:Art. 7235.

Site-1 protease-activated formation of lysosomal targeting motifs is independent of the lipogenic transcription control
Klünder S, Heeren J, Markmann S, Santer R, Braulke T, Pohl S
J LIPID RES. 2015;56(8):1625-32.

The trouble with validity: what is part of it and what is not?
Knorr M, Klusmann D
MED EDUC. 2015;49(6):550-2.

Apolipoprotein E promotes lipid accumulation and differentiation in human adipocytes
Lasrich D, Bartelt A, Grewal T, Heeren J
EXP CELL RES. 2015;337(1):94-102.

Diabetes prevalence in NZO females depends on estrogen action on liver fat content
Lubura M, Hesse D, Krämer M, Hallahan N, Schupp M, Loeffelholz C, Kriebel J, Rudovich N, Pfeiffer A, John C, Scheja L, Heeren J, Koliaki C, Roden M, Schürmann A
AM J PHYSIOL-ENDOC M. 2015;309(12):E968-E980.

Lrp1/LDL receptor play critical roles in mannose 6-phosphate-independent lysosomal enzyme targeting
Markmann S, Thelen M, Cornils K, Schweizer M, Brocke-Ahmadinejad N, Willnow T, Heeren J, Gieselmann V, Braulke T, Kollmann K
TRAFFIC. 2015.

Calcium Signalling Triggered by NAADP in T Cells Determines Cell Shape and Motility During Immune Synapse Formation
Nebel M, Zhang B, Odoardi F, Flügel A, Potter B, Guse A
Messenger (Los Angel). 2015;4(1):104-111.

Determination of liver-specific r2 * of a highly monodisperse USPIO by (59) Fe iron core-labeling in mice at 3 T MRI
Raabe N, Forberich E, Freund B, Bruns O, Heine M, Kaul M, Tromsdorf U, Herich L, Nielsen P, Reimer R, Hohenberg H, Weller H, Schumacher U, Adam G, Ittrich H
CONTRAST MEDIA MOL I. 2015;10:153-62.

Arginine and NASH--do macrophages deliver the first hit?
Scheja L, Kluwe J
J HEPATOL. 2015;62(2):260-1.

A Modular Framework for Post-Processing and Analysis of Fluorescence Microscopy Image Sequences of Subcellular Calcium Dynamics
Schetelig D, Wolf I, Diercks B, Fliegert R, Guse A, Schlaefer A, Werner R
2015. Bildverarbeitung für die Medizin 2015. Handels H, Deserno T, Meinzer H, Tolxdorff T (Hrsg.). 1. Aufl. Berlin Heidelberg: Springer, 401-406.

The new InsP3Kinase inhibitor BIP-4 is competitive to InsP3 and blocks proliferation and adhesion of lung cancer cells
Schröder D, Tödter K, Gonzalez B, Franco-Echevarría E, Rohaly G, Blechner C, Lin H, Mayr G, Windhorst S
BIOCHEM PHARMACOL. 2015;96(2):143-50.

Genetic Dissection of Tissue-Specific Apolipoprotein E Function for Hypercholesterolemia and Diet-Induced Obesity
Wagner T, Bartelt A, Schlein C, Heeren J
PLOS ONE. 2015;10(12):.

Introduction of the HAM-Nat examination – applicants and students admitted to the Medical Faculty in 2012-2014.
Werwick K, Winkler-Stuck K, Hampe W, Albrecht P, Robra B
GMS J MED EDU. 2015;32(5):Doc53.

Frontrunners of T cell activation: Initial, localized Ca2+ signals mediated by NAADP and the type 1 ryanodine receptor
Wolf I, Diercks B, Gattkowski E, Czarniak F, Kempski J, Werner R, Schetelig D, Mittrücker H, Schumacher V, von Osten M, Lodygin D, Flügel A, Fliegert R, Guse A
SCI SIGNAL. 2015;8(398):Art. ra102.

Determining the association between adipokine expression in multiple tissues and phenotypic features of non-alcoholic fatty liver disease in obesity
Wolfs M, Gruben N, Rensen S, Verdam F, Greve J, Driessen A, Wijmenga C, Buurman W, Franke L, Scheja L, Koonen D, Shiri-Sverdlov R, van Haeften T, Hofker M, Fu J
NUTR DIABETES. 2015;5:Art. e146.

Cooperative Feature Selection in Personalized Medicine
Zühlke D, Grunst G, Röser K
2015. Decision Making: Uncertainty, Imperfection, Deliberation and Scalability. Guy T, Kárný M, Wolpert D (Hrsg.). 1. Aufl. Springer International Publishing, 119-144.

Homozygosity for a partial deletion of apoprotein A-V signal peptide results in intracellular missorting of the protein and chylomicronemia in a breast-fed infant
Albers K, Schlein C, Wenner K, Lohse P, Bartelt A, Heeren J, Santer R, Merkel M
ATHEROSCLEROSIS. 2014;233(1):97-103.

Hepatic lipase is expressed by osteoblasts and modulates bone remodeling in obesity
Bartelt A, Beil T, Müller B, Koehne T, Yorgan T, Heine M, Yilmaz T, Ruether W, Heeren J, Schinke T, Niemeier A
BONE. 2014;62:90-98.

Adipose tissue browning and metabolic health
Bartelt A, Heeren J
NAT REV ENDOCRINOL. 2014;10(1):24-36.

TGF-β-dependent induction of CD4⁺CD25⁺Foxp3⁺ Tregs by liver sinusoidal endothelial cells
Carambia A, Freund B, Schwinge D, Heine M, Laschtowitz A, Huber S, Wraith D, Korn T, Schramm C, Lohse A, Heeren J, Herkel J
J HEPATOL. 2014;61(3):594-9.

Dichloroacetate prevents restenosis in preclinical animal models of vessel injury
Deuse T, Hua X, Wang D, Maegdefessel L, Heeren J, Scheja L, Bolaños J, Rakovic A, Spin J, Stubbendorff M, Ikeno F, Länger F, Zeller T, Schulte-Uentrop L, Stoehr A, Itagaki R, Haddad F, Eschenhagen T, Blankenberg S, Kiefmann R, Reichenspurner H, Velden J, Klein C, Yeung A, Robbins R, Tsao P, Schrepfer S
NATURE. 2014;509(7502):641-644.

GMA-Jahrestagung 2014 in Hamburg - Ankündigung
Hampe W, Kuhnigk O
GMS J MED EDU. 2014;31(2 Doc13):1-4.

Selectins mediate small cell lung cancer systemic metastasis
Heidemann F, Schildt A, Schmid K, Bruns O, Riecken K, Jung C, Ittrich H, Wicklein D, Reimer R, Fehse B, Heeren J, Lüers G, Schumacher U, Heine M
PLOS ONE. 2014;9(4):e92327.

The cell-type specific uptake of polymer-coated or micelle-embedded QDs and SPIOs does not provoke an acute pro-inflammatory response in the liver
Heine M, Bartelt A, Bruns O, Bargheer D, Giemsa A, Freund B, Scheja L, Waurisch C, Eychmüller A, Reimer R, Weller H, Nielsen P, Heeren J
BEILSTEIN J NANOTECH. 2014;5:1432-1440.

Cutting costs of multiple mini-interviews - changes in reliability and efficiency of the Hamburg medical school admission test between two applications
Hissbach J, Sehner S, Harendza S, Hampe W
BMC MED EDUC. 2014;14:54.

A liquid chromatography-tandem mass spectrometry-based method for the simultaneous determination of hydroxy sterols and bile acids
John C, Werner P, Worthmann A, Wegner K, Tödter K, Scheja L, Rohn S, Heeren J, Fischer M
J CHROMATOGR A. 2014;1371:184-195.

Gadospin f-enhanced magnetic resonance imaging for diagnosis and monitoring of atherosclerosis: validation with transmission electron microscopy and x-ray fluorescence imaging in the apolipoprotein e-deficient mouse
Jung C, Dučić T, Reimer R, Koziolek E, Kording F, Heine M, Adam G, Ittrich H, Kaul M
MOL IMAGING. 2014;13:1-10.

Intraperitoneal Injection Improves the Uptake of Nanoparticle-Labeled High-Density Lipoprotein to Atherosclerotic Plaques Compared With Intravenous Injection: A Multimodal Imaging Study in ApoE Knockout Mice
Jung C, Kaul M, Bruns O, Dučić T, Freund B, Heine M, Reimer R, Meents A, Salmen S, Weller H, Nielsen P, Adam G, Heeren J, Ittrich H
CIRC-CARDIOVASC IMAG. 2014;7(2):303-11.

Multiple mini-interviews: same concept, different approaches
Knorr M, Hissbach J
MED EDUC. 2014;48(12):1157-1175.

Prediction of practical performance in preclinical laboratory courses - the return of wire bending for admission of dental students in Hamburg
Kothe C, Hissbach J, Hampe W
GMS J MED EDU. 2014;31(2):Doc22.

Speed mentoring: establishing successful mentoring relationships
Kurré J, Schweigert E, Kulms G, Guse A
MED EDUC. 2014;48(11):1131.

Binding of hepatitis B virus to its cellular receptor alters the expression profile of genes of bile acid metabolism
Oehler N, Volz T, Bhadra O, Kah J, Allweiss L, Giersch K, Bierwolf J, Riecken K, Pollok J, Lohse A, Fehse B, Petersen J, Urban S, Lütgehetmann M, Heeren J, Dandri M
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Mechanisms of plasma non-transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients
Porter J, Walter P, Neumayr L, Evans P, Bansal S, Garbowski M, Weyhmiller M, Harmatz P, Wood J, Miller J, Byrnes C, Weiss G, Seifert M, Grosse R, Grabowski D, Schmidt A, Fischer R, Nielsen P, Niemeyer C, Vichinsky E
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Cholesterol Regulates Syntaxin 6 Trafficking at trans-Golgi Network Endosomal Boundaries
Reverter M, Rentero C, Garcia-Melero A, Hoque M, Vilà de Muga S, Alvarez-Guaita A, Conway J, Wood P, Cairns R, Lykopoulou L, Grinberg D, Vilageliu L, Bosch M, Heeren J, Blasi J, Timpson P, Pol A, Tebar F, Murray R, Grewal T, Enrich C
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High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice
Rinninger F, Heine M, Singaraja R, Hayden M, Brundert M, Ramakrishnan R, Heeren J
J LIPID RES. 2014;55(9):1914-1924.

Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism
Shin A, Fasshauer M, Filatova N, Grundell L, Zielinski E, Zhou J, Scherer T, Lindtner C, White P, Lapworth A, Ilkayeva O, Knippschild U, Wolf A, Scheja L, Grove K, Smith R, Qian W, Lynch C, Newgard C, Buettner C
CELL METAB. 2014;20(5):898-909.

Synthesis of radioactively labelled CdSe/CdS/ZnS quantum dots for in vivo experiments
Stachowski G, Bauer C, Waurisch C, Bargheer D, Nielsen P, Heeren J, Hickey S, Eychmüller A
BEILSTEIN J NANOTECH. 2014;5:2383-2387.

Design, Synthesis, and Chemical and Biological Properties of Cyclic ADP-4-Thioribose as a Stable Equivalent of Cyclic ADP-Ribose
Tsuzuki T, Takano S, Sakaguchi N, Kudoh T, Murayama T, Sakurai T, Hashii M, Higashida H, Weber K, Guse A, Kameda T, Hirokawa T, Kumaki Y, Arisawa M, Potter B, Shuto S
Messenger (Los Angel). 2014;3(1-2):35-51.

NAD derived second messengers: Role in spontaneous diastolic Ca(2+) transients
Warszta D, Nebel M, Fliegert R, Guse A
DNA REPAIR. 2014;23:69-78.

Effects of adipocyte lipoprotein lipase on de novo lipogenesis and white adipose tissue browning
Bartelt A, John C, Cherradi M, Niemeier A, Tödter K, Heeren J, Scheja L
BBA-MOL CELL BIOL L. 2013;1831(5):934-42.

Assessing language indicators across the lifespan within the German National Educational Panel Study (NEPS)
Berendes K, Weinert S, Zimmermann S, Artelt C
J EDUC RES ONLINE-JE. 2013;5(2):15-49.

Cycling assay for determining intracellular cyclic adp-ribose levels
Bruzzone S, Guse A
Cold Spring Harbor protocols. 2013;2013(6):564-8.

The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain
Carlo A, Gustafsen C, Mastrobuoni G, Nielsen M, Burgert T, Hartl D, Rohe M, Nykjaer A, Herz J, Heeren J, Kempa S, Petersen C, Willnow T
J NEUROSCI. 2013;33(1):358-70.

Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo.
Dieckmann M, Beil F, Müller B, Bartelt A, Marshall R, Köhne T, Amling M, Ruether W, Cooper J, Humphries S, Herz J, Niemeier A
J BONE MINER RES. 2013;28(2):236-245.

Pharmacological characterization of 1-nitrosocyclohexyl acetate, a long-acting nitroxyl donor that shows vasorelaxant and antiaggregatory effects
Donzelli S, Fischer G, King B, Niemann C, DuMond J, Heeren J, Wieboldt H, Baldus S, Gerloff C, Eschenhagen T, Carrier L, Böger R, Espey M
J PHARMACOL EXP THER. 2013;344(2):339-47.

De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health
Eissing L, Scherer T, Tödter K, Knippschild U, Greve J, Buurman W, Pinnschmidt H, Rensen S, Wolf A, Bartelt A, Heeren J, Buettner C, Scheja L
NAT COMMUN. 2013;4:1528.

Measuring Ca2+ release evoked by cyclic adp-ribose
Guse A
Cold Spring Harbor protocols. 2013;2013(6):574-8.

N-terminal tagging of two-pore channels interferes with NAADP action
Guse A
BIOCHEM J. 2013;453(1):e1-2.

NAADP signaling revisited
Guse A, Wolf I, Fliegert R
CURR TOP MED CHEM. 2013;13(23):2978-90.

Novel aspects of brown adipose tissue biology
Heeren J, Münzberg H
ENDOCRIN METAB CLIN. 2013;42(1):89-107.

TNFα-mediated liver destruction by Kupffer cells and Ly6Chi monocytes during Entamoeba histolytica infection
Helk E, Bernin H, Ernst T, Ittrich H, Jacobs T, Heeren J, Tacke F, Tannich E, Lotter H
PLOS PATHOG. 2013;9(1):e1003096.

Malignant H1299 tumour cells preferentially internalize iron-bound inositol hexakisphosphate
Helmis C, Blechner C, Lin H, Schweizer M, Mayr G, Nielsen P, Windhorst S
BIOSCIENCE REP. 2013;33(5):.

Measuring CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) activity by reverse-phase HPLC
Kirchberger T, Guse A
Cold Spring Harbor protocols. 2013;2013(6):569-73.

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b
Kornfeld J, Baitzel C, Könner A, Nicholls H, Vogt M, Herrmanns K, Scheja L, Haumaitre C, Wolf A, Knippschild U, Seibler J, Cereghini S, Heeren J, Stoffel M, Brüning J
NATURE. 2013;494(7435):111-5.

The Hamburg selection procedure for dental students - introduction of the HAM-Nat as subject-specific test for study aptitude
Kothe C, Hissbach J, Hampe W
GMS J MED EDU. 2013;30(4):Doc46.

Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists
Moreau C, Kirchberger T, Swarbrick J, Bartlett S, Fliegert R, Yorgan T, Bauche A, Harneit A, Guse A, Potter B
J MED CHEM. 2013;56(24):10079-102.

Inhibition of mitogen-activated protein kinase Erk1/2 promotes protein degradation of ATP binding cassette transporters A1 and G1 in CHO and HuH7 cells
Mulay V, Wood P, Manetsch M, Darabi M, Cairns R, Hoque M, Chan K, Reverter M, Alvarez-Guaita A, Rye K, Rentero C, Heeren J, Enrich C, Grewal T
PLOS ONE. 2013;8(4):e62667.

Audio podcasts in practical courses in biochemistry - cost-efficient e-learning in a well-proven format from radio broadcasting
Münch-Harrach D, Kothe C, Hampe W
GMS J MED EDU. 2013;30(4):Doc44.

Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling and arrhythmias in the heart evoked by β-adrenergic stimulation
Nebel M, Schwoerer A, Warszta D, Siebrands C, Limbrock A, Swarbrick J, Fliegert R, Weber K, Bruhn S, Hohenegger M, Geisler A, Herich L, Schlegel S, Carrier L, Eschenhagen T, Potter B, Ehmke H, Guse A
J BIOL CHEM. 2013;288(22):16017-30.

Increased expression of transthyretin in leptin-deficient ob/ob mice is not causative for their major phenotypic abnormalities.
Rendenbach C, Ganswindt S, Seitz S, Barvencik F, Hübner A, Baranowsky A, Streichert T, Niemeier A, Heeren J, Amling M, Bartelt A, Schinke T
J NEUROENDOCRINOL. 2013;25(1):14-22.

On health literacy and health outcomes: background, impact, and future directions
Rudd R, Groene O, Navarro-Rubio M
Revista de calidad asistencial : organo de la Sociedad Espanola de Calidad Asistencial. 2013;28(3):188-92.

A mathematical model of T lymphocyte calcium dynamics derived from single transmembrane protein properties
Schmeitz C, Hernandez-Vargas E, Fliegert R, Guse A, Meyer-Hermann M
FRONT IMMUNOL. 2013;4:277.

Eisenquantifizierung mittels MRT bei Eisenüberladung
Schönnagel B, Fischer R, Nielsen P, Grosse R, Adam G, Yamamura J
ROFO-FORTSCHR RONTG. 2013;185(7):621-7.

Design and synthesis of cyclic ADP-4-thioribose as a stable equivalent of cyclic ADP-ribose, a calcium ion-mobilizing second messenger
Tsuzuki T, Sakaguchi N, Kudoh T, Takano S, Uehara M, Murayama T, Sakurai T, Hashii M, Higashida H, Weber K, Guse A, Kameda T, Hirokawa T, Kumaki Y, Potter B, Fukuda H, Arisawa M, Shuto S
ANGEW CHEM INT EDIT. 2013;52(26):6633-7.

Adenine Dinucleotide Second Messengers and T-lymphocyte Calcium Signaling
Wolf I, Fliegert R, Guse A
FRONT IMMUNOL. 2013;4:259.

Leber- und Milzvolumenmessung in Patienten mit Eisenüberladung im Vergleich zu Lebereisen mit quantitativer MRT und biomagnetischer Suszeptometrie
Yamamura J, Schönnagel B, Berliner C, Brehmer M, Nielsen P, Adam G, Fischer R
ROFO-FORTSCHR RONTG. 2013;185(S 01):VO211_2.

Eisenmessung mittels MRT-R2* und Kalibrierung in der Milz
Yamamura J, Schönnagel B, Brehmer M, Berliner C, Nielsen P, Adam G, Fischer R
ROFO-FORTSCHR RONTG. 2013;185(S 01):VO307_6.

Kardiale, pankreatische und hepatische Eisenmessung bei Patienten mit hereditärer Hämochromatose
Yamamura J, Schönnagel B, Brehmer M, Berliner C, Nielsen P, Adam G, Fischer R
ROFO-FORTSCHR RONTG. 2013;185(S 01):VO402_3.

Serum levels of fetal antigen 1 in extreme nutritional States.
Andries A, Niemeier A, Støving R, Abdallah B, Wolf A, Hørder K, Kassem M
ISRN Endocrinol. 2012;2012:592648.

Effect of one-year vitamin C- and E-supplementation on cerebrospinal fluid oxidation parameters and clinical course in Alzheimer's disease.
Arlt S, Müller-Thomsen T, Beisiegel U, Kontush A
NEUROCHEM RES. 2012;37(12):2706-2714.

The holy grail of metabolic disease: brown adipose tissue.
Bartelt A, Heeren J
CURR OPIN LIPIDOL. 2012;23(3):190-195.

A new, powerful player in lipoprotein metabolism: brown adipose tissue.
Bartelt A, Merkel M, Heeren J
J MOL MED. 2012;90(8):887-893.

Osteochondritis dissecans of the tarsal navicular bone: a case report.
Beil F, Bruns J, Habermann C, Rüther W, Niemeier A
J AM PODIAT MED ASSN. 2012;102(4):338-342.

Dissection of minimal sequence requirements for rhoptry membrane targeting in the malaria parasite
Cabrera A, Herrmann S, Warszta D, Santos J, John Peter A, Kono M, Debrouver S, Jacobs T, Spielmann T, Ungermann C, Soldati-Favre D, Gilberger T
TRAFFIC. 2012;13(10):1335-50.

A simple and widely applicable method to 59Fe-radiolabel monodisperse superparamagnetic iron oxide nanoparticles for in vivo quantification studies.
Freund B, Tromsdorf U, Bruns O, Heine M, Giemsa A, Bartelt A, Salmen S, Raabe N, Heeren J, Ittrich H, Reimer R, Hohenberg H, Schumacher U, Weller H, Nielsen P
ACS NANO. 2012;6(8):7318-7325.

Impaired LDL receptor-related protein 1 translocation correlates with improved dyslipidemia and atherosclerosis in apoE-deficient mice.
Gordts P, Bartelt A, Nilsson S, Annaert W, Christoffersen C, Nielsen L, Heeren J, Roebroek A
PLOS ONE. 2012;7(6):38330.

Linking NAADP to ion channel activity: a unifying hypothesis.
Guse A, Andreas H
SCI SIGNAL. 2012;5(221):18.

Losen statt warten. Wie die Wartezeit von Bewerbern auf Medizinstudienplätze verkürzt werden könnte
Hampe W, Hissbach J, Werner G, Thews O
Forschung & Lehre. 2012;19(6):480-481.

Nanocrystals, a new tool to study lipoprotein metabolism and atherosclerosis.
Heeren J, Bruns O
CURR PHARM BIOTECHNO. 2012;13(2):365-372.

High interstitial fluid pressure is associated with low tumour penetration of diagnostic monoclonal antibodies applied for molecular imaging purposes.
Heine M, Freund B, Nielsen P, Jung C, Reimer R, Hohenberg H, Zangemeister-Wittke U, Wester H, Lüers G, Schumacher U
PLOS ONE. 2012;7(5):36258.

Suitability of the HAM-Nat test and TMS module "basic medical-scientific understanding" for medical school selection.
Hissbach J, Feddersen L, Sehner S, Hampe W
GMS J MED EDU. 2012;29(5):72.

The GTPase ARFRP1 controls the lipidation of chylomicrons in the Golgi of the intestinal epithelium.
Jaschke A, Chung B, Hesse D, Kluge R, Zahn C, Moser M, Petzke K, Brigelius-Flohé R, Puchkov D, Koepsell H, Heeren J, Joost H, Schürmann A
HUM MOL GENET. 2012;21(14):3128-3142.

Welche Fähigkeiten brauchen Zahnmedizinstudierende? Auswahltests in Hamburg und Graz
Kothe C, Korbmacher H, Hissbach J, Ithaler D, Kahl-Nieke B, Reibnegger G, Hampe W
DZZ - Deut Zahnärztl Z. 2012;67(4):254-259.

Homepages of German medical faculties--an overview.
Kuhnigk O, Tiller D, Harendza S, Hampe W
GMS J MED EDU. 2012;29(4):59.

Low density lipoprotein receptor-related protein 1 dependent endosomal trapping and recycling of apolipoprotein E.
Laatsch A, Panteli M, Sornsakrin M, Hoffzimmer B, Grewal T, Heeren J
PLOS ONE. 2012;7(1):29385.

Platelet lysate suppresses the expression of lipocalin-type prostaglandin D2 synthase that positively controls adipogenic differentiation of human mesenchymal stromal cells.
Lange C, Brunswig-Spickenheier B, Eissing L, Scheja L
EXP CELL RES. 2012;318(18):2284-2296.

Bioavailability of chromium(III)-supplements in rats and humans.
Laschinsky N, Kottwitz K, Freund B, Dresow B, Fischer R, Nielsen P
BIOMETALS. 2012;25(5):1051-1060.

Mannose 6 dephosphorylation of lysosomal proteins mediated by acid phosphatases Acp2 and Acp5.
Makrypidi G, Damme M, Müller-Loennies S, Trusch M, Schmidt B, Schlüter H, Heeren J, Lübke T, Saftig P, Braulke T
MOL CELL BIOL. 2012;32(4):774-782.

The role of apolipoprotein E in bone metabolism.
Niemeier A, Schinke T, Heeren J, Amling M
BONE. 2012;50(2):518-524.

Triacylglycerol-rich lipoproteins protect lipoprotein lipase from inactivation by ANGPTL3 and ANGPTL4.
Nilsson S, Anderson F, Ericsson M, Larsson M, Makoveichuk E, Lookene A, Heeren J, Olivecrona G
Biochim Biophys Acta. 2012;1821(10):1370-1378.

Nicotinic acid adenine dinucleotide phosphate (NAADP) degradation by alkaline phosphatase.
Schmid F, Fliegert R, Westphal T, Bauche A, Guse A
J BIOL CHEM. 2012;287(39):32525-32534.

The 5-phosphatase OCRL mediates retrograde transport of the mannose 6-phosphate receptor by regulating a Rac1-cofilin signalling module.
van Rahden V, Brand K, Najm J, Heeren J, Heeren J, Braulke T, Kutsche K, Kutsche K
HUM MOL GENET. 2012;21(23):5019-5038.

Nicotinic Acid Adenine Dinucleotide 2'-Phosphate (NAADP) Binding Proteins in T-Lymphocytes
Walseth T, Lin-Moshier Y, Weber K, Marchant J, Slama J, Guse A
Messenger (Los Angel). 2012;1(1):86-94.

Brown adipose tissue activity controls triglyceride clearance.
Bartelt A, Bruns O, Reimer R, Hohenberg H, Ittrich H, Peldschus K, Kaul M, Tromsdorf U, Weller H, Waurisch C, Eychmüller A, Gordts P, Rinninger F, Brügelmann K, Freund B, Nielsen P, Merkel M, Heeren J
NAT MED. 2011;17(2):200-205.

Altered endocannabinoid signalling after a high-fat diet in Apoe(-/-) mice: relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance.
Bartelt A, Orlando P, Mele C, Ligresti A, Tödter K, Scheja L, Heeren J, Di Marzo V
DIABETOLOGIA. 2011;54(11):2900-2910.

Scavenger receptor CD36 mediates uptake of high density lipoproteins in mice and by cultured cells.
Brundert M, Heeren J, Merkel M, Carambia A, Herkel J, Groitl P, Dobner T, Ramakrishnan R, Moore K, Rinninger F
J LIPID RES. 2011;52(4):745-758.

PML isoforms I and II participate in PML-dependent restriction of HSV-1 replication.
Cuchet D, Sykes A, Nicolas A, Orr A, Murray J, Sirma H, Heeren J, Bartelt A, Everett R
J CELL SCI. 2011;124(2):280-291.

A novel type of congenital hypochromic anemia associated with a nonsense mutation in the STEAP3/TSAP6 gene.
Grandchamp B, Hetet G, Kannengiesser C, Oudin C, Beaumont C, Rodrigues-Ferreira S, Amson R, Telerman A, Nielsen P, Kohne E, Balser C, Heimpel H
BLOOD. 2011;118(25):6660-6666.

Investigations on the usefulness of CEACAMs as potential imaging targets for molecular imaging purposes.
Heine M, Nollau P, Maßlo C, Nielsen P, Freund B, Bruns O, Reimer R, Hohenberg H, Peldschus K, Ittrich H, Schumacher U
PLOS ONE. 2011;6(12):28030.

Studienbewerberauswahl – Probates Mittel gegen den Ärztemangel?
Hissbach J, Hampe W
Arzt und Krankenhaus. 2011;2:42-44.

Dimensionality and predictive validity of the HAM-Nat, a test of natural sciences for medical school admission.
Hissbach J, Klusmann D, Hampe W
BMC MED EDUC. 2011;11:83.

Reliability of a science admission test (HAM-Nat) at Hamburg medical school.
Hissbach J, Klusmann D, Hampe W
GMS J MED EDU. 2011;28(3):44.

Histological Analysis
Johansson C, Jimbo R, Röser K
2011. Comprehensive Biomaterials. Ducheyne P, Healy K, Hutmacher D, Grainger D, Kirkpatrick C (Hrsg.). 1. Aufl. Elsevier Limited, 215-233.

[Energy, brown adipose tissue, obesity].
Merkel M, Heeren J
DEUT MED WOCHENSCHR. 2011;136(11):548-550.

Enhanced increase of omega-3 index in response to long-term n-3 fatty acid supplementation from triacylglycerides versus ethyl esters.
Neubronner J, Schuchardt J, Kressel G, Merkel M, von Schacky C, Hahn A
EUR J CLIN NUTR. 2011;65(2):247-254.

Apolipoprotein A-V; a potent triglyceride reducer.
Nilsson S, Heeren J, Olivecrona G, Merkel M
ATHEROSCLEROSIS. 2011;219(1):15-21.

Short-term activation of liver X receptors inhibits osteoblasts but long-term activation does not have an impact on murine bone in vivo.
Prawitt J, Beil F, Marshall R, Bartelt A, Rüther W, Heeren J, Amling M, Staels B, Niemeier A
BONE. 2011;48(2):339-346.

Attitudes of patients with schizophrenia and depression to psychiatric research: a study in seven European countries.
Schäfer I, Burns T, Fleischhacker W, Galderisi S, Rybakowski J, Libiger J, Rössler W, Molodynski A, Edlinger M, Piegari G, Jela H, Gorna K, Jaeger M, Fett A, Hissbach J, Naber D
SOC PSYCH PSYCH EPID. 2011;46(2):159-165.

Beneficial effects of IKKε-deficiency on body weight and insulin sensitivity are lost in high fat diet-induced obesity in mice.
Scheja L, Heese B, Seedorf K
BIOCHEM BIOPH RES CO. 2011;407(2):288-294.

Brain insulin controls adipose tissue lipolysis and lipogenesis.
Scherer T, O'Hare J, Diggs-Andrews K, Schweiger M, Cheng B, Lindtner C, Zielinski E, Vempati P, Su K, Dighe S, Milsom T, Puchowicz M, Scheja L, Zechner R, Fisher S, Previs S, Buettner C
CELL METAB. 2011;13(2):183-194.

Role for LAMP-2 in endosomal cholesterol transport.
Schneede A, Schmidt C, Hölttä-Vuori M, Heeren J, Willenborg M, Blanz J, Domanskyy M, Breiden B, Brodesser S, Landgrebe J, Sandhoff K, Ikonen E, Saftig P, Eskelinen E
J CELL MOL MED. 2011;15(2):280-295.

Moderate doses of EPA and DHA from re-esterified triacylglycerols but not from ethyl-esters lower fasting serum triacylglycerols in statin-treated dyslipidemic subjects: Results from a six month randomized controlled trial.
Schuchardt J, Neubronner J, Kressel G, Merkel M, von Schacky C, Hahn A
PROSTAG LEUKOTR ESS. 2011;85(6):381-386.

Plasma triglycerides after oral glucose load specifically associate with metabolic risk markers in healthy type 2 diabetes offspring.
Vossen M, Tödter K, Altenburg C, Beisiegel U, Scheja L
ATHEROSCLEROSIS. 2011;217(1):214-219.

Estimation of LDL cholesterol by the Friedewald formula during an oral glucose tolerance test.
Vossen M, Vettorazzi E, Wegscheider K, Laatsch A
DIABETIC MED. 2011;28(11):1433-1434.

Differences and similarities between obsessive and ruminative thoughts in obsessive-compulsive and depressed patients: a comparative study.
Wahl K, Schönfeld S, Hissbach J, Küsel S, Zurowski B, Moritz S, Hohagen F, Kordon A
J BEHAV THER EXP PSY. 2011;42(4):454-461.

Ras/mitogen-activated protein kinase (MAPK) signaling modulates protein stability and cell surface expression of scavenger receptor SR-BI.
Wood P, Mulay V, Darabi M, Chan K, Heeren J, Pol A, Lambert G, Rye K, Enrich C, Grewal T
J BIOL CHEM. 2011;286(26):23077-23092.

Pancreatic exocrine function and cardiac iron in patients with iron overload and with thalassemia.
Yamamura J, Grosse R, Jarisch A, Janka-Schaub G, Nielsen P, Adam G, Fischer R
PEDIATR BLOOD CANCER. 2011;57(4):674-676.

Letzte Aktualisierung aus dem FIS: 29.11.2024 - 23:32 Uhr