- Nachwuchsgruppenleiterin
Fachgebiete
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Immunologie
Tätigkeitsschwerpunkte
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The Myeloid Systems Immunology Lab focuses on the ontogeny of mononuclear phagocytes – what drives cell fate decisions in the bone marrow vs. tissues. As development and functional imprinting are closely tied together processes, we are investigating how perturbation, e.g. by viral infections and the cellular environment impacts these decisions. To address these questions, we combine single-cell genomics, spatial transcriptomics, and high-parameter flow cytometry with machine learning approaches.
Publikationen
Guidelines for mouse and human DC functional assays
Clausen B, Amon L, Backer R, Berod L, Bopp T, Brand A, Burgdorf S, Chen L, Da M, Distler U, Dress R, Dudziak D, Dutertre C, Eich C, Gabele A, Geiger M, Ginhoux F, Giusiano L, Godoy G, Hamouda A, Hatscher L, Heger L, Heidkamp G, Hernandez L, Jacobi L, Kaszubowski T, Kong W, Lehmann C, Lopez Lopez T, Mahnke K, Nitsche D, Renkawitz J, Reza R, Saez P, Schlautmann L, Schmitt M, Seicher A, Sielaff M, Sparwasser T, Stoitzer P, Tchitashvili G, Tenzer S, Tochoedo N, Vurnek D, Zink F, Hieronymus T
EUR J IMMUNOL. 2023;53(12):e2249925.
Dendritic cell type 3 arises from Ly6C+ monocyte-dendritic cell progenitors
Liu Z, Haiting W, Ziyi L, Dress R, Yiwen Z, Shuangyan Z, De Feo D, Kong W, Peiliang C, Shin A, Piot C, Yu J, Yaqi G, Mingnan Z, Caixa G, Honglin W, Vétillard M, Guermonprez P, Kwok I, Ng L, Chakarov S, Schlitzer A, Becher B, Dutertre C, Bing S, Ginhoux F
IMMUNITY. 2023;56(8):1761-1777.e6.
Proteasome inhibitor bortezomib stabilizes and activates p53 in hematopoietic stem/progenitors and double-negative T cells in vivo
Xue Y, Louis B, Dress R, Murad K, Ginhoux F, Barker N, Lane D
P NATL ACAD SCI USA. 2023;120(13):e2219978120.
Characterization of Developmental Trajectories of Dendritic Cell Hematopoiesis Through Single-Cell RNA Sequencing Methods
Dress R, Ginhoux F
2023. Dendritic Cells. Sisirak V (Hrsg.). 1. Aufl. New York, NY: Humana Press, 375-385.
Network analysis of large-scale ImmGen and Tabula Muris datasets highlights metabolic diversity of tissue mononuclear phagocytes
Gainullina A, Mogilenko D, Huang L, Todorov H, Narang V, Kim K, Yng L, Kent A, Jia B, Seddu K, Krchma K, Wu J, Crozat K, Tomasello E, Dress R, See P, Scott C, Gibbings S, Bajpai G, Desai J, Maier B, This S, Wang P, Aguilar S, Poupel L, Dussaud S, Zhou T, Angeli V, Blander J, Choi K, Dalod M, Dzhagalov I, Gautier E, Jakubzick C, Lavine K, Lionakis M, Paidassi H, Sieweke M, Ginhoux F, Guilliams M, Benoist C, Merad M, Randolph G, Sergushichev A, Artyomov M
CELL REP. 2023;42(2):112046.
Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration
Silvin A, Uderhardt S, Piot C, Da Mesquita S, Yang K, Geirsdottir L, Mulder K, Eyal D, Liu Z, Bridlance C, Thion M, Zhang X, Kong W, Deloger M, Fontes V, Weiner A, Ee R, Dress R, Hang J, Balachander A, Chakarov S, Malleret B, Dunsmore G, Cexus O, Chen J, Garel S, Dutertre C, Amit I, Kipnis J, Ginhoux F
IMMUNITY. 2022;55(8):1448-1465.e6.
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)
Cossarizza A, Chang H, Radbruch A, Abrignani S, Addo R, Akdis M, Andrä I, Andreata F, Annunziato F, Arranz E, Bacher P, Bari S, Barnaba V, Barros-Martins J, Baumjohann D, Beccaria C, Bernardo D, Boardman D, Borger J, Böttcher C, Brockmann L, Burns M, Busch D, Cameron G, Cammarata I, Cassotta A, Chang Y, Chirdo F, Christakou E, Čičin-Šain L, Cook L, Corbett A, Cornelis R, Cosmi L, Davey M, De Biasi S, De Simone G, Del Zotto G, Delacher M, Di Rosa F, Santo J, Diefenbach A, Dong J, Dörner T, Dress R, Dutertre C, Eckle S, Eede P, Evrard M, Falk C, Feuerer M, Fillatreau S, Fiz-Lopez A, Follo M, Foulds G, Fröbel J, Gagliani N, Galletti G, Gangaev A, Garbi N, Garrote J, Geginat J, Gherardin N, Gibellini L, Ginhoux F, Godfrey D, Gruarin P, Haftmann C, Hansmann L, Harpur C, Hayday A, Heine G, Hernández D, Herrmann M, Hoelsken O, Huang Q, Huber S, Huber J, Huehn J, Hundemer M, Hwang W, Iannacone M, Ivison S, Jäck H, Jani P, Keller B, Kessler N, Ketelaars S, Knop L, Knopf J, Koay H, Kobow K, Kriegsmann K, Kristyanto H, Krueger A, Kuehne J, Kunze-Schumacher H, Kvistborg P, Kwok I, Latorre D, Lenz D, Levings M, Lino A, Liotta F, Long H, Lugli E, MacDonald K, Maggi L, Maini M, Mair F, Manta C, Manz R, Mashreghi M, Mazzoni A, McCluskey J, Mei H, Melchers F, Melzer S, Mielenz D, Monin L, Moretta L, Multhoff G, Muñoz L, Muñoz-Ruiz M, Muscate F, Natalini A, Neumann K, Ng L, Niedobitek A, Niemz J, Almeida L, Notarbartolo S, Ostendorf L, Pallett L, Patel A, Percin G, Peruzzi G, Pinti M, Pockley A, Pracht K, Prinz I, Pujol-Autonell I, Pulvirenti N, Quatrini L, Quinn K, Radbruch H, Rhys H, Rodrigo M, Romagnani C, Saggau C, Sakaguchi S, Sallusto F, Sanderink L, Sandrock I, Schauer C, Scheffold A, Scherer H, Schiemann M, Schildberg F, Schober K, Schoen J, Schuh W, Schüler T, Schulz A, Schulz S, Schulze J, Simonetti S, Singh J, Sitnik K, Stark R, Starossom S, Stehle C, Szelinski F, Tan L, Tarnok A, Tornack J, Tree T, van Beek J, van de Veen W, van Gisbergen K, Vasco C, Verheyden N, von Borstel A, Ward-Hartstonge K, Warnatz K, Waskow C, Wiedemann A, Wilharm A, Wing J, Wirz O, Wittner J, Yang J, Yang J
EUR J IMMUNOL. 2021;51(12):2708-3145.
Polymersomes as Stable Nanocarriers for a Highly Immunogenic and Durable SARS-CoV-2 Spike Protein Subunit Vaccine
Lam J, Khan A, Cornell T, Chia T, Dress R, Yeow W, Mohd-Ismail N, Venkataraman S, Ng K, Tan Y, Anderson D, Ginhoux F, Nallani M
ACS NANO. 2021;15(10):15754-15770.
Monocytes and macrophages in severe COVID-19 - friend, foe or both?
Dress R, Ginhoux F
IMMUNOL CELL BIOL. 2021;99(6):561-564.
TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses
Caronni N, Piperno G, Simoncello F, Romano O, Vodret S, Yanagihashi Y, Dress R, Dutertre C, Bugatti M, Bourdeley P, Del Prete A, Schioppa T, Mazza E, Collavin L, Zacchigna S, Ostuni R, Guermonprez P, Vermi W, Ginhoux F, Bicciato S, Nagata S, Benvenuti F
NAT COMMUN. 2021;12(1):.
Next generation vaccine platform: polymersomes as stable nanocarriers for a highly immunogenic and durable SARS-CoV-2 spike protein subunit vaccine
Lam J, Khan A, Cornell T, Dress R, Chia T, Yeow W, Mohd-Ismail N, Venkatraman S, Ng K, Tan Y, Anderson D, Ginhoux F, Nallani M
bioRxiv. 2021.
Open Source ImmGen: network perspective on metabolic diversity among mononuclear phagocytes
Gainullina A, Huang L, Todorov H, Kim K, Yng L, Kent A, Jia B, Seddu K, Krchma K, Wu J, Crozat K, Tomasello E, Narang V, Dress R, See P, Scott C, Gibbings S, Bajpai G, Desai J, Maier B, This S, Wang P, Aguilar S, Poupel L, Dussaud S, Zhou T, Angeli V, Blander J, Choi K, Dalod M, Dzhagalov I, Gautier E, Jakubzick C, Lavine K, Lionakis M, Paidassi H, Sieweke M, Ginhoux F, Guilliams M, Benoist C, Merad M, Randolph G, Sergushichev A, Artyomov M
bioRxiv. 2020.
ImmGen at 15
Aguilar S, Aguilar O, Allan R, Amir E, Angeli V, Artyomov M, Asinovski N, Astarita J, Austen K, Bajpai G, Barrett N, Baysoy A, Benoist C, Bellemare-Pelletier A, Berg B, Best A, Bezman N, Blair D, Blander J, Bogunovic M, Brennan P, Brenner M, Brown B, Buechler M, Buenrostro J, Casanova M, Choi K, Chow A, Chudnovskiy A, Cipoletta D, Cohen N, Collins J, Colonna M, Cook A, Costello J, Cremasco V, Crowl T, Crozat K, Cruse R, D’Angelo J, Dalod M, Davis S, Demiralp C, Deng T, Desai J, Desland F, Dhainaut M, Ding J, Doedens A, Dominguez C, Doran G, Dress R, Dustin M, Dwyer D, Dzhagalov I, Elpek K, Ergun A, Ericson J, Esomonu E, Fairfax K, Fletcher A, Frascoli M, Fuchs A, Gainullina A, Gal-Oz S, Gallagher M, Gautier E, Gazit R, Gibbings S, Giraud M, Ginhoux F, Goldrath A, Gotthardt D, Gray D, Greter M, Grieshaber-Bouyer R, Guilliams M, Haidermota S, Hardy R, Hashimoto D, Helft J, Hendricks D, Heng T, Hill J, Hyatt G, Idoyaga J, Jakubzick C, Jarjoura J, Jepson D, Jia B, Jianu R, Johanson T, Jordan S, Jojic V, Jordan S, Kamimura Y, Kana V, Kang J, Kapoor V, Kenigsberg E, Kent A, Kim C, Kim E, Kim F, Kim J, Kim K, Kiner E, Knell J, Koller D, Kozinn L, Krchma K, Kreslavsky T, Kronenberg M, Kwan W, Laidlaw D, Lam V, Lanier L, Laplace C, Lareau C, Lavin Y, Lavine K, Leader A, Leboeuf M, Lee J, Lee J, Li B, Li H, Li Y, Lionakis M, Luche H, Lynch L, Magen A, Maier B, Malhotra D, Malhotra N, Malissen M, Maslova A, Mathis D, McFarland A, Merad M, Meunier E, Miller J, Milner J, Mingueneau M, Min-Oo G, Monach P, Moodley D, Mortha A, Morvan M, Mostafavi S, Muller S, Muus C, Nabekura T, Rao T, Narang V, Narayan K, Ner-Gaon H, Nguyen Q, Nigrovic P, Novakovsky G, Nutt S, Omilusik K, Ortiz-Lopez A, Paidassi H, Paik H, Painter M, Paynich M, Peng V, Potempa M, Pradhan R, Price J, Qi Y, Qi Y, Quon S, Ramirez R, Ramanan D, Randolph G, Regev A, Rhoads A, Robinette M, Rose S, Rossi D, Rothamel K, Sachidanandam R, Sathe P, Scott C, Seddu K, See P, Sergushichev A, Shaw L, Shay T, Shemesh A, Shinton S, Shyer J, Sieweke M, Smillie C, Spel L, Spidale N, Stifano G, Subramanian A, Sun J, Sylvia K, Tellier J, This S, Tomasello E, Todorov H, Turley S, Vijaykumar B, Wagers A, Wakamatsu E, Wang C, Wang P, Wroblewska A, Wu J, Yang E, Yang L, Yim A, Yng L, Yoshida H, Yu B, Zhou Y, Zhu Y, Ziemkiewicz C
NAT IMMUNOL. 2020;21(7):700-703.
Towards the better understanding of myelopoiesis using single-cell technologies
Dress R, Liu Z, Ginhoux F
MOL IMMUNOL. 2020;122:186-192.
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
Cossarizza A, Chang H, Radbruch A, Acs A, Adam D, Adam-Klages S, Agace W, Aghaeepour N, Akdis M, Allez M, Almeida L, Alvisi G, Anderson G, Andrä I, Annunziato F, Anselmo A, Bacher P, Baldari C, Bari S, Barnaba V, Barros-Martins J, Battistini L, Bauer W, Baumgart S, Baumgarth N, Baumjohann D, Baying B, Bebawy M, Becher B, Beisker W, Benes V, Beyaert R, Blanco A, Boardman D, Bogdan C, Borger J, Borsellino G, Boulais P, Bradford J, Brenner D, Brinkman R, Brooks A, Busch D, Büscher M, Bushnell T, Calzetti F, Cameron G, Cammarata I, Cao X, Cardell S, Casola S, Cassatella M, Cavani A, Celada A, Chatenoud L, Chattopadhyay P, Chow S, Christakou E, Čičin-Šain L, Clerici M, Colombo F, Cook L, Cooke A, Cooper A, Corbett A, Cosma A, Cosmi L, Coulie P, Cumano A, Cvetkovic L, Dang V, Dang-Heine C, Davey M, Davies D, De Biasi S, Del Zotto G, Dela Cruz G, Delacher M, Della Bella S, Dellabona P, Deniz G, Dessing M, Di Santo J, Diefenbach A, Dieli F, Dolf A, Dörner T, Dress R, Dudziak D, Dustin M, Dutertre C, Ebner F, Eckle S, Edinger M, Eede P, Ehrhardt G, Eich M, Engel P, Engelhardt B, Erdei A, Esser C, Everts B, Evrard M, Falk C, Fehniger T, Felipo-Benavent M, Ferry H, Feuerer M, Filby A, Filkor K, Fillatreau S, Follo M, Förster I, Foster J, Foulds G, Frehse B, Frenette P, Frischbutter S, Fritzsche W, Galbraith D, Gangaev A, Garbi N, Gaudilliere B, Gazzinelli R, Geginat J, Gerner W, Gherardin N, Ghoreschi K, Gibellini L, Ginhoux F, Goda K, Godfrey D, Goettlinger C, González-Navajas J, Goodyear C, Gori A, Grogan J, Grummitt D, Grützkau A, Haftmann C, Hahn J, Hammad H, Hämmerling G, Hansmann L, Hansson G, Harpur C, Hartmann S, Hauser A, Hauser A, Haviland D, Hedley D, Hernández D, Herrera G, Herrmann M, Hess C, Höfer T, Hoffmann P, Hogquist K, Holland T, Höllt T, Holmdahl R, Hombrink P, Houston J, Hoyer B, Huang B, Huang F, Huber J, Huehn J, Hundemer M, Hunter C, Hwang W, Iannone A, Ingelfinger F, Ivison S, Jäck H, Jani P, Jávega B, Jonjic S, Kaiser T, Kalina T, Kamradt T, Kaufmann S, Keller B, Ketelaars S, Khalilnezhad A, Khan S, Kisielow J, Klenerman P, Knopf J, Koay H, Kobow K, Kolls J, Kong W, Kopf M, Korn T, Kriegsmann K, Kristyanto H, Kroneis T, Krueger A, Kühne J, Kukat C, Kunkel D, Kunze-Schumacher H, Kurosaki T, Kurts C, Kvistborg P, Kwok I, Landry J, Lantz O, Lanuti P, LaRosa F, Lehuen A, LeibundGut-Landmann S, Leipold M, Leung L, Levings M, Lino A, Liotta F, Litwin V, Liu Y, Ljunggren H, Lohoff M, Lombardi G, Lopez L, López-Botet M, Lovett-Racke A, Lubberts E, Luche H, Ludewig B, Lugli E, Lunemann S, Maecker H, Maggi L, Maguire O, Mair F, Mair K, Mantovani A, Manz R, Marshall A, Martínez-Romero A, Martrus G, Marventano I, Maslinski W, Matarese G, Mattioli A, Maueröder C, Mazzoni A, McCluskey J, McGrath M, McGuire H, McInnes I, Mei H, Melchers F, Melzer S, Mielenz D, Miller S, Mills K, Minderman H, Mjösberg J, Moore J, Moran B, Moretta L, Mosmann T, Müller S, Multhoff G, Muñoz L, Münz C, Nakayama T, Nasi M, Neumann K, Ng L, Niedobitek A, Nourshargh S, Núñez G, O'Connor J, Ochel A, Oja A, Ordonez D, Orfao A, Orlowski-Oliver E, Ouyang W, Oxenius A, Palankar R, Panse I, Pattanapanyasat K, Paulsen M, Pavlinic D, Penter L, Peterson P, Peth C, Petriz J, Piancone F, Pickl W, Piconese S, Pinti M, Pockley A, Podolska M, Poon Z, Pracht K, Prinz I, Pucillo C, Quataert S, Quatrini L, Quinn K, Radbruch H, Radstake T, Rahmig S, Rahn H, Rajwa B, Ravichandran G, Raz Y, Rebhahn J, Recktenwald D, Reimer D, Reis E Sousa C, Remmerswaal E, Richter L, Rico L, Riddell A, Rieger A, Robinson J, Romagnani C, Rubartelli A, Ruland J, Saalmüller A, Saeys Y, Saito T, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sandrock I, Santoni A, Sanz R, Saresella M, Sautes-Fridman C, Sawitzki B, Schadt L, Scheffold A, Scherer H, Schiemann M, Schildberg F, Schimisky E, Schlitzer A, Schlosser J, Schmid S, Schmitt S, Schober K, Schraivogel D, Schuh W, Schüler T, Schulte R, Schulz A, Schulz S, Scottá C, Scott-Algara D, Sester D, Shankey T, Silva-Santos B, Simon A, Sitnik K, Sozzani S, Speiser D, Spidlen J, Stahlberg A, Stall A, Stanley N, Stark R, Stehle C, Steinmetz T, Stockinger H, Takahama Y, Takeda K, Tan L, Tárnok A, Tiegs G, Toldi G, Tornack J, Traggiai E, Trebak M, Tree T, Trotter J, Trowsdale J, Tsoumakidou M, Ulrich H, Urbanczyk S, van de Veen W, van den Broek M, van der Pol E, Van Gassen S, Van Isterdael G, van Lier R, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk H, von Borstel A, von Volkmann K, Waisman A, Walker R, Wallace P, Wang S, Wang X, Ward M, Ward-Hartstonge K, Warnatz K, Warnes G, Warth S, Waskow C, Watson J, Watzl C, Wegener L, Weisenburger T, Wiedemann A, Wienands J, Wilharm A, Wilkinson R, Willimsky G, Wing J, Winkelmann R, Winkler T, Wirz O, Wong A, Wurst P, Yang J, Yang J, Yazdanbakhsh M, Yu L, Yue A, Zhang H, Zhao Y, Ziegler S, Zielinski C, Zimmermann J, Zychlinsky A
EUR J IMMUNOL. 2019;49(10):1457-1973.
Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells
Liu Z, Gu Y, Chakarov S, Bleriot C, Kwok I, Chen X, Shin A, Huang W, Dress R, Dutertre C, Schlitzer A, Chen J, Ng L, Wang H, Liu Z, Su B, Ginhoux F
CELL. 2019;178(6):1509-1525.
Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage.
Dress R, Dutertre C, Giladi A, Schlitzer A, Low I, Shadan N, Tay A, Lum J, Mohd Kairi M, Hwang Y, Becht E, Cheng Y, Chevrier M, Larbi A, Newell E, Amit I, Chen J, Ginhoux F
NAT IMMUNOL. 2019;2019(20):.
Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance
Braza M, van Leent M, Lameijer M, Sanchez-Gaytan B, Arts R, Pérez-Medina C, Conde P, Garcia M, Gonzalez-Perez M, Brahmachary M, Fay F, Kluza E, Kossatz S, Dress R, Salem F, Rialdi A, Reiner T, Boros P, Strijkers G, Calcagno C, Ginhoux F, Marazzi I, Lutgens E, Nicolaes G, Weber C, Swirski F, Nahrendorf M, Fisher E, Duivenvoorden R, Fayad Z, Netea M, Mulder W, Ochando J
IMMUNITY. 2018;49(5):819-828.e6.
Homeostatic control of dendritic cell numbers and differentiation.
Dress R, Wong A, Ginhoux F
IMMUNOL CELL BIOL. 2018.
Identification of a novel Dlg2 isoform differentially expressed in IFNβ-producing plasmacytoid dendritic cells.
Ali S, Hoven A, Dress R, Schaal H, Alferink J, Scheu S
BMC GENOMICS. 2018.
Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis
Giladi A, Paul F, Herzog Y, Lubling Y, Weiner A, Yofe I, Jaitin D, Cabezas-Wallscheid N, Dress R, Ginhoux F, Trumpp A, Tanay A, Amit I
NAT CELL BIOL. 2018;20(7):836-846.
Enterococcus faecalis Promotes Innate Immune Suppression and Polymicrobial Catheter-Associated Urinary Tract Infection.
Tien B, Goh H, Chong K, Bhaduri-Tagore S, Holec S, Dress R, Ginhoux F, Ingersoll M, Williams R, Kline K
INFECT IMMUN. 2017.
Cutting Edge: IFN-β Expression in the Spleen Is Restricted to a Subpopulation of Plasmacytoid Dendritic Cells Exhibiting a Specific Immune Modulatory Transcriptome Signature.
Bauer J, Dress R, Schulze A, Dresing P, Ali S, Deenen R, Alferink J, Scheu S
J IMMUNOL. 2016.
Staphylococcus aureus hemolysin A disrupts cell-matrix adhesions in human airway epithelial cells
Hermann I, Räth S, Ziesemer S, Volksdorf T, Dress R, Gutjahr M, Müller C, Beule A, Hildebrandt J
AM J RESP CELL MOL. 2015;52(1):14-24.
IRF4 and BATF are critical for CD8(+) T-cell function following infection with LCMV
Grusdat M, McIlwain D, Xu H, Pozdeev V, Knievel J, Crome S, Robert-Tissot C, Dress R, Pandyra A, Speiser D, Lang E, Maney S, Elford A, Hamilton S, Scheu S, Pfeffer K, Bode J, Mittrücker H, Lohoff M, Huber M, Häussinger D, Ohashi P, Mak T, Lang K, Lang P
CELL DEATH DIFFER. 2014;21(7):1050-60.
Letzte Aktualisierung aus dem FIS: 27.11.2024 - 23:33 Uhr