- Geschäftsführende Oberärztin
- Wissenschaftliche Mitarbeiterin
- Fachärztin für Hals-Nasen-Ohren-Heilkunde
- Medikamentöse Tumortherapie
Fachgebiete
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Hals-Nasen-Ohrenheilkunde
Tätigkeitsschwerpunkte
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Klinische Studien
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Medikamentöse Tumortherapie
Mitgliedschaften
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Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e.V.
Publikationen
A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts
LANCET DIGIT HEALTH. 2024;6(7):e507-e519.
Traditional risk factors and nodal yield-still relevant with high-quality risk-adapted adjuvant treatment for locally advanced head and neck cancer?
Butt Y, Tennstedt P, Busch C, Hanken H, Krüll A, Petersen C, Tribius S
STRAHLENTHER ONKOL. 2023;199(3):284-292.
SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study
ANAESTHESIA. 2022;77(1):28-39.
Tissue Microarray Analyses Suggest Axl as a Predictive Biomarker in HPV-Negative Head and Neck Cancer
Busch C, Hagel C, Becker B, Oetting A, Möckelmann N, Droste C, Möller-Koop C, Witt M, Blaurock M, Loges S, Rothkamm K, Betz C, Münscher A, Clauditz T, Rieckmann T
CANCERS. 2022;14(7):.
Detection of stage I HPV-driven oropharyngeal cancer in asymptomatic individuals in the Hamburg City Health Study using HPV16 E6 serology - A proof-of-concept study
Busch C, Hoffmann A, Viarisio D, Becker B, Rieckmann T, Betz C, Bender N, Schroeder L, Hussein Y, Petersen E, Jagodzinski A, Schäfer I, Burandt E, Lang Kuhs K, Pawlita M, Waterboer T, Brenner N
ECLINICALMEDICINE. 2022;53:.
Early relapse detection by monitoring of circulating cell-free DNA in patients with localized head and neck squamous cell carcinomaA subgroup analysis of the multicenter randomized clinical trial IMSTAR-HN
Jonas H, Simnica D, Bußmann L, Zech H, Doescher J, Laban S, Busch C, Binder M
ORAL ONCOL. 2022;126:.
Patient derived ex vivo tissue slice cultures demonstrate a profound DNA double-strand break repair defect in HPV-positive oropharyngeal head and neck cancer
Zech H, Berger J, Mansour W, Nordquist L, von Bargen C, Bußmann L, Oetting A, Christiansen S, Möckelmann N, Böttcher A, Busch C, Petersen C, Betz C, Rothkamm K, Kriegs M, Köcher S, Rieckmann T
RADIOTHER ONCOL. 2022;168:138-146.
Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery
BJS OPEN. 2021;5(6):.
Head and neck cancer surgery during the COVID-19 pandemic: An international, multicenter, observational cohort study
CANCER-AM CANCER SOC. 2021;127(14):2476-2488.
Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic
BRIT J SURG. 2021;108(1):88-96.
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
BRIT J SURG. 2021;108(9):1056-1063.
Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study.
ANAESTHESIA. 2021;76(6):748-758.
Kinomic comparison of snap frozen and ex vivo-cultured head and neck tumors
Berger J, Zech H, Hoffer K, von Bargen C, Nordquist L, Bussmann L, Gatzemeier F, Busch C, Möckelmann N, Münscher A, Betz C, Petersen C, Rothkamm K, Rieckmann T, Köcher S, Kriegs M
ORAL ONCOL. 2021;123:.
Rational surgical neck management in total laryngectomy for advanced stage laryngeal squamous cell carcinomas
Böttcher A, Betz C, Bartels S, Schönnagel B, Münscher A, Bußmann L, Busch C, Knopke S, Bibiza-Freiwald E, Möckelmann N
J CANCER RES CLIN. 2021;147(2):549-559.
Analyzing tyrosine kinase activity in head and neck cancer by functional kinomics: Identification of hyperactivated Src-family kinases as prognostic markers and potential targets
Bußmann L, Hoffer K, von Bargen C, Droste C, Lange T, Kemmling J, Schröder-Schwarz J, Vu A, Akingunsade L, Nollau P, Rangarajan S, de Wijn R, Oetting A, Müller C, Böckelmann L, Zech H, Berger J, Möckelmann N, Busch C, Böttcher A, Gatzemeier F, Klinghammer K, Simnica D, Binder M, Struve N, Rieckmann T, Schumacher U, Clauditz T, Betz C, Petersen C, Rothkamm K, Münscher A, Kriegs M
INT J CANCER. 2021;149(5):1166 - 1180.
Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study
Glasbey J, Bhangu A
J CLIN ONCOL. 2021;39(1):66-78.
Parotid sparing and quality of life in long-term survivors of locally advanced head and neck cancer after intensity-modulated radiation therapy
Tribius S, Haladyn S, Hanken H, Busch C, Krüll A, Petersen C, Bergelt C
STRAHLENTHER ONKOL. 2021;197(3):219-230.
Delaying surgery for patients with a previous SARS-CoV-2 infection
BRIT J SURG. 2020;107(12):e601-e602.
Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans: Elective surgery during the SARS-CoV-2 pandemic
BRIT J SURG. 2020;107(11):1440-1449.
Comparative effectiveness trial of transoral head and neck surgery followed by adjuvant radio(chemo)therapy versus primary radiochemotherapy for oropharyngeal cancer (TopROC)
Bußmann L, Laban S, Wittekindt C, Stromberger C, Tribius S, Möckelmann N, Böttcher A, Betz C, Klussmann J, Budach V, Muenscher A, Busch C
BMC CANCER. 2020;20(1):701.
Rationale and Design of the Hamburg City Health Study
Jagodzinski A, Johansen C, Koch-Gromus U, Aarabi G, Adam G, Anders S, Augustin M, der Kellen R, Beikler T, Behrendt C, Betz C, Bokemeyer C, Borof K, Briken P, Busch C, Büchel C, Brassen S, Debus E, Eggers L, Fiehler J, Gallinat J, Gellißen S, Gerloff C, Girdauskas E, Gosau M, Graefen M, Härter M, Harth V, Heidemann C, Heydecke G, Huber T, Hussein Y, Kampf M, von dem Knesebeck O, Konnopka A, König H, Kromer R, Kubisch C, Kühn S, Loges S, Löwe B, Lund G, Meyer C, Nagel L, Nienhaus A, Pantel K, Petersen E, Püschel K, Reichenspurner H, Sauter G, Scherer M, Scherschel K, Schiffner U, Schnabel R, Schulz H, Smeets R, Sokalskis V, Spitzer M, Terschüren C, Thederan I, Thoma T, Thomalla G, Waschki B, Wegscheider K, Wenzel J, Wiese S, Zyriax B, Zeller T, Blankenberg S
EUR J EPIDEMIOL. 2020;35(2):169-181.
Influence of radiation dose to pharyngeal constrictor muscles on late dysphagia and quality of life in patients with locally advanced oropharyngeal carcinoma
Mogadas S, Busch C, Pflug C, Hanken H, Krüll A, Petersen C, Tribius S
STRAHLENTHER ONKOL. 2020;196(6):522-529.
Prognostic factors for lymphedema in patients with locally advanced head and neck cancer after combined radio(chemo)therapy- results of a longitudinal study
Tribius S, Pazdyka H, Tennstedt P, Busch C, Hanken H, Krüll A, Petersen C
ORAL ONCOL. 2020;109:104856.
Mass Spectrometric Comparison of HPV-Positive and HPV-Negative Oropharyngeal Cancer
Wurlitzer M, Möckelmann N, Kriegs M, Vens M, Omidi M, Hoffer K, Bargen C, Möller-Koop C, Witt M, Droste C, Oetting A, Petersen H, Busch C, Münscher A, Schlüter H, Clauditz T, Rieckmann T
CANCERS. 2020;12(6):.
Moderne Therapiekonzepte bei Kopf-Hals-Tumoren
Zech H, Busch C
TUMORDIAGN THER. 2020;41(8):521-526.
Phase III study of nivolumab alone or combined with ipilimumab as immunotherapy versus standard of care in resectable head and neck squamous cell carcinoma
Zech H, Moeckelmann N, Boettcher A, Muenscher A, Binder M, Vettorazzi E, Bokemeyer C, Schafhausen P, Betz C, Busch C
FUTURE ONCOL. 2020;16(36):3035-3043.
Tumor volume as a predictive parameter in the sequential therapy (induction chemotherapy) of head and neck squamous cell carcinomas
Bohlen M, Busch C, Sehner S, Forterre F, Bier J, Berliner C, Bußmann L, Münscher A
EUR ARCH OTO-RHINO-L. 2019;276(4):1183-1189.
Immuntherapie von Kopf-Hals-Tumoren: Highlights der ASCO-Jahrestagung 2019
Doescher J, Busch C, Wollenberg B, Dietz A, Würdemann N, Schuler P, Hoffmann T, Laban S
HNO. 2019;67(12):905-911.
Therapie der rezidivierten und fernmetastasierten Plattenepithelkarzinome des Kopf-Hals-Bereichs: Highlights des ASCO-Meetings 2019
Zech H, Laban S, Schafhausen P, Bussmann L, Betz C, Busch C
HNO. 2019;67(12):898-904.
Therapie der rezidivierten und fernmetastasierten Plattenepithelkarzinome des Kopf-Hals-Bereichs: Highlights des ASCO-Meetings 2018
Bußmann L, Münscher A, Busch C
HNO. 2018;66(12):907-912.
Current studies of immunotherapy in head and neck cancer
Dogan V, Rieckmann T, Münscher A, Busch C
CLIN OTOLARYNGOL. 2018;43(1):13-21.
Comparison of PapilloCheck and Linear Array to Detect and Differentiate Human Papillomaviruses in Cervical and Tonsillar Smears from Females with Cervical Intraepithelial Lesions
Grimm D, Woelber L, Prieske K, Schmalfeldt B, Kürti S, Busch C, Teudt I, Brummer O, Mueller V, Meyer T
EUR J MICROBIOL IMMU. 2018;8(4):107-111.
Highlights der ASCO Jahrestagung 2018 zur Immuntherapie von Kopf-Hals-Tumoren
Laban S, Doescher J, Busch C, Wollenberg B, Dietz A, Würdemann N, Schuler P, Hoffmann T
HNO. 2018;66(12):880-887.
Socioeconomic status and quality of life in patients with locally advanced head and neck cancer
Tribius S, Meyer M, Pflug C, Hanken H, Busch C, Krüll A, Petersen C, Bergelt C
STRAHLENTHER ONKOL. 2018;194(8):737-749.
Induction chemotherapy followed by radiochemotherapy for locally advanced head and neck cancer as an individual treatment approach-Feasibility, safety and retrospective survival analysis in twenty-three patients
Busch C, Girke J, Tribius S, Bussmann L, Knecht R, Schafhausen P, Lörincz B, Münscher A
CLIN OTOLARYNGOL. 2017;42(6):1392-1396.
G2-checkpoint targeting and radiosensitization of HPV/p16-positive HNSCC cells through the inhibition of Chk1 and Wee1
Busch C, Kröger M, Jensen J, Kriegs M, Gatzemeier F, Petersen C, Münscher A, Rothkamm K, Rieckmann T
RADIOTHER ONCOL. 2017;122(2):260-266.
Oral Human Papillomavirus in Women With High-Grade Cervical Intraepithelial Neoplasia
Woelber L, Breuer J, Meyer T, Vettorazzi E, Prieske K, Bohlmann I, Busch C, Teudt I, Brummer O, Mueller V, Schmalfeldt B, Grimm D
J LOW GENIT TRACT DI. 2017;21(3):177-183.
Liquid biopsy monitoring uncovers acquired RAS-mediated resistance to cetuximab in a substantial proportion of patients with head and neck squamous cell carcinoma
Braig F, Voigtländer M, Schieferdecker A, Busch C, Laban S, Grob T, Kriegs M, Knecht R, Bokemeyer C, Binder M
ONCOTARGET. 2016;7(28):42988-42995.
Similar cisplatin sensitivity of HPV-positive and -negative HNSCC cell lines
Busch C, Becker B, Kriegs M, Gatzemeier F, Krüger K, Möckelmann N, Fritz G, Petersen C, Knecht R, Rothkamm K, Rieckmann T
ONCOTARGET. 2016;7(24):35832-35842.
Postoperative antibiotic prophylaxis in clean-contaminated head and neck oncologic surgery: a retrospective cohort study
Busch C, Knecht R, Münscher A, Matern J, Dalchow C, Lörincz B
EUR ARCH OTO-RHINO-L. 2016;273(9):2805-11.
Immuntherapeutische Studien bei Kopf-Hals-Tumoren: Highlights der ASCO-Jahrestagung 2016
Busch C, Laban S, Knecht R, Hoffmann T
HNO. 2016;64(10):708-16.
Therapie der rezidivierten und fernmetastasierten Kopf-Hals-Tumoren: Highlights des ASCO-Meetings 2016
Bußmann L, Busch C, Knecht R
HNO. 2016;64(10):723-30.
Perspectives in chemosensitivity and chemoresistance assays and their implementation in head and neck cancer
Bussmann L, Busch C, Lörincz B, Rieckmann T, Block A, Knecht R
EUR ARCH OTO-RHINO-L. 2016;273(12):4073-4080.
Immuntherapie des HNSCC: Quo vadis?
Döscher J, Busch C, Schuler P, Laban S
HNO. 2016;64(10):700-7.
Studienergebnisse zur Primärtherapie von Kopf-Hals-Tumoren: Highlights der ASCO-Jahrestagung 2016
Gliese A, Busch C, Knecht R
HNO. 2016;64(10):717-22.
Curative treatment of head and neck squamous cell carcinoma: Organ preservation strategies in clinical routine in German-speaking countries
Kurzweg T, Kimmeyer J, Knecht R, Hoffmann T, Busch C, Lörincz B, Schuler P, Laban S
HNO. 2016;64(7):501-7.
Palliative treatment standards for head and neck squamous cell carcinoma: Survey of clinical routine in German-speaking countries
Laban S, Kimmeyer J, Knecht R, Hoffmann T, Busch C, Veit J, Möckelmann N, Kurzweg T
HNO. 2016;64(7):487-93.
Molecular targeting in combination with platinum-based chemoradiation in head and neck cancer treatment
Möckelmann N, Kriegs M, Lörincz B, Busch C, Knecht R
HEAD NECK-J SCI SPEC. 2016;38(Suppl 1):E2173-81.
Effect of sorafenib on cisplatin-based chemoradiation in head and neck cancer cells
Möckelmann N, Rieckmann T, Busch C, Becker B, Gleißner L, Hoffer K, Omniczynski M, Steinmeister L, Laban S, Grénman R, Petersen C, Rothkamm K, Dikomey E, Knecht R, Kriegs M
ONCOTARGET. 2016;7(17):23542-51.
The current role of systemic chemotherapy in the primary treatment of head and neck cancer
Busch C, Tribius S, Schafhausen P, Knecht R
CANCER TREAT REV. 2015;41(3):217-21.
Therapie der rezidivierten und fernmetastasierten Plattenepithelkarzinome des Kopf-Hals-Bereichs:Highlights des ASCO-Meetings 2015
Bußmann L, Busch C, Knecht R
HNO. 2015;63(9):620-4.
Die wichtigsten Studienergebnisse zur nichtchirurgischen Primärtherapie lokal fortgeschrittener Kopf‑Hals‑Tumoren: Highlights des ASCO-Kongresses 2015
Gliese A, Busch C, Knecht R
HNO. 2015;63(9):606-11.
Die wichtigsten Studienergebnisse zur nicht-chirurgischen Primärtherapie lokal fortgeschrittener Kopf-Hals-Tumoren: Highlights des ASCO-Meetings 2015
Gliese A, Busch C, Knecht R
HNO. 2015;63(9):606-611.
Erratum zu: Die wichtigsten Studienergebnisse in der Primärtherapie von Kopf-Hals-Tumoren : Highlights des ASCO-Meetings 2014
Gliese A, Busch C, Knecht R
HNO. 2015;63(11):767.
A comparison of hearing results following stapedotomy under local versus general anesthesia
Loewenthal M, Jowett N, Busch C, Knecht R, Dalchow C
EUR ARCH OTO-RHINO-L. 2015;272(9):2121-7.
Feasibility and safety of transoral robotic surgery (TORS) for early hypopharyngeal cancer: a subset analysis of the Hamburg University TORS-trial
Lörincz B, Busch C, Möckelmann N, Knecht R
EUR ARCH OTO-RHINO-L. 2015;272(10):2993-2998.
Initial learning curve of single-incision transaxillary robotic hemi- and total thyroidectomy--A single team experience from Europe
Lörincz B, Busch C, Möckelmann N, Knecht R
INT SURG. 2015;18:118-22.
Automatic periodic stimulation of the vagus nerve during single-incision transaxillary robotic thyroidectomy: Feasibility, safety, and first cases
Lörincz B, Möckelmann N, Busch C, Hezel M, Knecht R
HEAD NECK-J SCI SPEC. 2015;38(3):482-485.
Functional outcomes, feasibility, and safety of resection of transoral robotic surgery: Single-institution series of 35 consecutive cases of transoral robotic surgery for oropharyngeal squamous cell carcinoma
Lörincz B, Möckelmann N, Busch C, Knecht R
HEAD NECK-J SCI SPEC. 2015;37(11):1618-1624.
Two-Year Survival Analysis of 50 Consecutive Head and Neck Cancer Patients Treated with Transoral Robotic Surgery in a Single European Centre
Lörincz B, Möckelmann N, Busch C, Münscher A, Sehner S, Dalchow C, Knecht R
ANN SURG ONCOL. 2015;22:S1028-S1033.
Timing of neck dissection in patients undergoing transoral robotic surgery for head and neck cancer
Möckelmann N, Busch C, Münscher A, Knecht R, Lörincz B
EJSO-EUR J SURG ONC. 2015.
Die wichtigsten Studienergebnisse in der Primärtherapie von Kopf-Hals-Tumoren: Highlights des ASCO-Meetings 2014
Gliese A, Busch C, Knecht R
HNO. 2014;62(11):781-6.
The inhibition of PARP but not EGFR results in the radiosensitization of HPV/p16-positive HNSCC cell lines
Güster J, Weissleder S, Busch C, Kriegs M, Petersen C, Knecht R, Dikomey E, Rieckmann T
RADIOTHER ONCOL. 2014;113(3):345-51.
Therapie von Kopf-Hals-Karzinomen
Knecht R, Busch C, Lörincz B, Schafhausen P, Tribius S, Heiland M, Jenckel F, Münscher A, Petersen C, Bokemeyer C
Hamb Ärztebl. 2014;8:12-17.
Induktionschemotherapie bei lokal fortgeschrittenen Kopf-Hals-Karzinomen – pro
Knecht R, Busch C, Schafhausen P
DEUT MED WOCHENSCHR. 2014;139(41):2080.
Simultaneous cytoplasmic and nuclear protein expression of melanoma antigen-A family and NY-ESO-1 cancer-testis antigens represents an independent marker for poor survival in head and neck cancer
Laban S, Atanackovic D, Luetkens T, Knecht R, Busch C, Freytag M, Spagnoli G, Ritter G, Hoffmann T, Knuth A, Sauter G, Wilczak W, Blessmann M, Borgmann K, Münscher A, Clauditz T
INT J CANCER. 2014.
Therapie der rezidivierten und fernmetastasierten Plattenepithelkarzinome des Kopf-Hals-Bereichs: Highlights des ASCO-Meetings 2014
Zeller N, Busch C, Schafhausen P, Knecht R, Möckelmann N
HNO. 2014;62(11):787-92.
Hereditäre sensorineurale Schwerhörigkeit und Makrothrombozytopenie: Eine seltene Mutation des MYH9-Gens
Böttcher A, Knecht R, Busch C, Lörincz B, Dalchow C
HNO. 2013;61(2):159-60, 162-5.
HPV-positive HNSCC cell lines but not primary human fibroblasts are radiosensitized by the inhibition of Chk1
Busch C, Kriegs M, Laban S, Tribius S, Knecht R, Petersen C, Dikomey E, Rieckmann T
RADIOTHER ONCOL. 2013;108(3):495-9.
Expression of insulin-like growth factor II mRNA-binding protein 3 in squamous cell carcinomas of the head and neck
Clauditz T, Busch C, Gontarewicz A, Blessmann M, Tennstedt P, Borgmann K, Tribius S, Sauter G, Dalchow C, Knecht R, Münscher A, Wilczak W
J ORAL PATHOL MED. 2013;42(2):125-32.
New treatment strategies for HPV-positive head and neck cancer
Kofler B, Laban S, Busch C, Lörincz B, Knecht R
EUR ARCH OTO-RHINO-L. 2013.
Molecular targeting agents in the context of primary chemoradiation strategies.
Laban S, Busch C, Münscher A, Tribius S, Schafhausen P, Knecht R
HEAD NECK-J SCI SPEC. 2013;35(5):738-746.
Die wichtigsten Studienergebnisse der primären Radio-Chemo-Therapie von Kopf-Hals-Tumoren: Highlights des ASCO-Meetings 2013
Münscher A, Busch C, Schafhausen P, Tribius S, Knecht R
HNO. 2013;61(11):905-10.
HNSCC cell lines positive for HPV and p16 possess higher cellular radiosensitivity due to an impaired DSB repair capacity.
Rieckmann T, Tribius S, Grob T, Meyer F, Busch C, Petersen C, Dikomey E, Kriegs M
RADIOTHER ONCOL. 2013;107(2):242-246.
11q21 rearrangement is a frequent and highly specific genetic alteration in mucoepidermoid carcinoma
Clauditz T, Gontarewicz A, Wang C, Münscher A, Laban S, Tsourlakis M, Knecht R, Sauter G, Wilczak W
DIAGN MOL PATHOL. 2012;21(3):134-137.
[New aspects of primary radiochemotherapy in head and neck cancer : Highlights from the 2011 ASCO Congress].
Laban S, Wang C, Knecht R, Tribius S, Münscher A
HNO. 2012;60(5):393-397.
Die wichtigsten Studienergebnisse der primären Radiochemotherapie von Kopf-Hals-Tumoren: Highlights vom ASCO-Meeting 2012
Laban S, Zielinski V, Busch C, Münscher A, Schafhausen P, Tribius S, Knecht R
HNO. 2012;60(11):962-967.
Neue Aspekte zur aktuellen Therapie von Oropharynxkarzinomen: Highlights vom ASCO-Kongress 2012
Loewenthal M, Vitez E, Laban S, Münscher A, Güldenzoph B, Knecht R, Busch C
HNO. 2012;60(11):951-6.
[New aspects of current therapeutic strategies in oropharyngeal carcinoma: highlights of the 2012 ASCO meeting].
Löwenthal M, Vitez E, Laban S, Münscher A, Güldenzoph B, Knecht R, Busch C
HNO. 2012;60(11):951-956.
Current concepts of organ preservation in head and neck cancer.
Wang C, Knecht R
EUR ARCH OTO-RHINO-L. 2011;268(4):481-487.
Letzte Aktualisierung aus dem FIS: 29.11.2024 - 23:36 Uhr