UKE - Zentrum für Neuroendokrine Tumore

Arbeitsgruppe Tumorenvironment

Projekte:

1. STAT 3 Activation through Cancer-Associated Fibroblasts. Induction of Proliferation and Therapeutic Resistance to Everolimus in Neuroendocrine Tumors.

2. ATR Inhibition as a potential therapy for DAXX mutated neuroendocrine Neoplasms.

3. Streptozotocin resistant pancreatic neuroendocrine tumour cell lines as a tool to understand chemotherapy resistance in pNET.

4. Characterization of FGF/FGFR signalling as a central mitogenic pathway in neuroendocrine Neoplasms.

5. Immune cell interaction in pathogenesis and development of pNET.